Weight-Loss drug tirzepatide may help keep heart rhythm steady after ablation
NCT ID NCT07382024
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests whether tirzepatide, a drug used for diabetes and weight loss, can reduce the return of atrial fibrillation (AFib) after a heart procedure called catheter ablation. Overweight or obese adults with persistent AFib will receive either tirzepatide injections plus standard care, or standard care alone. The main goal is to see if the drug lowers the amount of time spent in AFib three months after the procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Tirzepatide
- What this could lead to
- If it works, this could point toward a way to lower the chance of AFib returning after ablation and improve weight and metabolic health.
- What could go wrong
- This is a small, early-phase trial with only 200 participants. The drug may not reduce AFib burden, and side effects like nausea or digestive issues are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
National Taiwan University Hospital Cardiovascular Center
Taipei, 100, Taiwan
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