Can a strict diet put type 2 diabetes into remission?
NCT ID NCT07748949
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This trial tests whether a low-calorie diet combined with intensive lifestyle coaching can help adults with type 2 diabetes achieve remission—meaning blood sugar levels return to normal without medication. Participants are randomly assigned to either the intervention or standard care. The intervention includes meal replacements, personalized meal plans, exercise, continuous glucose monitoring, and telemedicine support over six months. The study aims to see if this approach increases the chance of remission and improves overall metabolic health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Low-calorie diet combined with intensive lifestyle intervention using Integrated Personalized Diabetes Management (iPDM)
- What this could lead to
- If successful, this approach could offer a drug-free path to diabetes remission, potentially reducing or eliminating the need for glucose-lowering medications in some adults with type 2 diabetes.
- What could go wrong
- The trial is small (54 participants) and the remission may not be durable or achievable for everyone. The intensive diet and lifestyle changes require significant commitment, and results may not generalize to broader populations.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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King Chulalongkorn Memorial Hospital
RECRUITINGBangkok, 10330, Thailand
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