Hormone clue may unmask kidney danger in diabetes

This study investigates whether people with type 2 diabetes who have or are at risk for chronic kidney disease produce too much aldosterone, a hormone that regulates salt and blood pressure. Participants undergo several suppression tests—including oral sodium, saline infusion, and medication challenges—to measure how much aldosterone their bodies produce independently of normal triggers. The goal is to understand if this hidden hormone excess is linked to kidney damage, which could lead to better detection and treatment strategies.