Can a simple numbing drug make heart ablation less disruptive?

NCT ID NCT07354217

Not yet recruiting Symptom relief Sponsor: National Taiwan University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether giving lidocaine through an IV can reduce diaphragm twitching and coughing during a procedure called pulse field ablation for atrial fibrillation. Sixty adults with AFib will be randomly assigned to receive lidocaine or a placebo (saline). The goal is to see if lidocaine makes the procedure smoother and more comfortable.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lidocaine
What this could lead to: If it works, this could make pulse field ablation more comfortable and reduce procedure interruptions for atrial fibrillation patients.
What could go wrong: This is a small Phase 4 study (60 people) testing a known drug for a new use during a procedure. It may not show clear benefit, and lidocaine can have side effects like low blood pressure or allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LIDOCAINE PULSED-FIELD ABLATION

Contacts and locations

Locations

National Taiwan University Hospita

Taipei, 100, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.