Fewer radiation sessions may be just as effective for thymic tumors after surgery

NCT ID NCT07693855

First seen Jul 09, 2026 · Last updated Jul 17, 2026 · Updated 3 times

Summary

This clinical trial is testing a shorter, more intense course of radiation therapy (called hypofractionated radiotherapy) for people who have had surgery for thymic epithelial tumors, including thymoma and thymic carcinoma. The goal is to see if this approach can keep the tumor from coming back in the chest while reducing side effects and protecting heart and lung function. Participants receive either proton or photon radiation over about 3 weeks, with the type chosen by their doctor and them together. The study will track tumor control, side effects, and quality of life for five years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Radiation therapy (proton or photon)
What this could lead to
If successful, this shorter radiation schedule could become a standard option after thymoma surgery, offering similar tumor control with fewer hospital visits and potentially less long-term toxicity.
What could go wrong
This is a single-arm, non-randomized study with only 69 participants, so results may not apply broadly. Radiation still carries risks of heart, lung, or esophageal side effects, and long-term outcomes are not yet known.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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Locations

  • China Medical University Hospital

    Taichung, Taiwan

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Taiwan University Cancer Center

    Taipei, 106037, Taiwan

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Taiwan University Hospital

    Taipei, 100229, Taiwan

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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