Could two hormones beat one for IVF success?
NCT ID NCT07269392
First seen Jan 06, 2026 · Last updated Jun 19, 2026 · Updated 31 times
Summary
This study tests whether giving two hormones (HCG and GnRH agonist) together before transferring a frozen embryo can improve implantation rates. About 170 women aged 24-45 undergoing modified natural cycle frozen embryo transfer will be randomly assigned to receive either the standard HCG trigger or the dual trigger. The main goal is to see if more embryos successfully implant with the dual trigger.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
GnRH agonist (added to HCG for ovulation trigger)
What this could lead to
If it works, this could improve the chance of embryo implantation in frozen embryo transfer cycles, potentially increasing pregnancy rates.
What could go wrong
This is a Phase 4 trial with only 170 participants, so results may not apply to all IVF patients. The dual trigger may not improve outcomes and could cause side effects.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.