Could two hormones beat one for IVF success?

NCT ID NCT07269392

Not yet recruiting Disease control Sponsor: National Taiwan University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving two hormones (HCG and GnRH agonist) together before transferring a frozen embryo can improve implantation rates. About 170 women aged 24-45 undergoing modified natural cycle frozen embryo transfer will be randomly assigned to receive either the standard HCG trigger or the dual trigger. The main goal is to see if more embryos successfully implant with the dual trigger.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: GnRH agonist (added to HCG for ovulation trigger)
What this could lead to: If it works, this could improve the chance of embryo implantation in frozen embryo transfer cycles, potentially increasing pregnancy rates.
What could go wrong: This is a Phase 4 trial with only 170 participants, so results may not apply to all IVF patients. The dual trigger may not improve outcomes and could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EMBRYO TRANSFER IN VITRO FERTILIZATION (IVF)

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