Can ultrasound reveal how knee ligaments change with osteoarthritis?
NCT ID NCT07744789
First seen Aug 04, 2026 · Last updated Aug 07, 2026 · Updated 3 times
Summary
This study uses a special ultrasound technique called shear wave elastography to measure the stiffness of knee ligaments in healthy adults and in people with knee osteoarthritis. The goal is to establish normal stiffness values across different ethnic groups and to see how ligament stiffness changes after clinically indicated injection therapy. Participants will undergo ultrasound exams and clinical assessments, with follow-up for those receiving injections.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Shear wave elastography (ultrasound imaging) and ultrasound-guided injection therapy (corticosteroid, hypertonic dextrose, or platelet-rich plasma)
- What this could lead to
- If successful, this could establish normal knee ligament stiffness values across ethnicities and reveal how these change with osteoarthritis and treatment, potentially improving diagnosis and therapy monitoring.
- What could go wrong
- This is an observational and exploratory study, not a treatment trial. The findings may not directly change clinical practice, and the injection therapies are given based on routine care, not as part of a controlled experiment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Taiwan University Hospital, Bei-Hu Branch
RECRUITINGTaipei, Taipei City, 108, Taiwan
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