Can ultrasound reveal how knee ligaments change with osteoarthritis?

NCT ID NCT07744789

First seen Aug 04, 2026 · Last updated Aug 07, 2026 · Updated 3 times

Summary

This study uses a special ultrasound technique called shear wave elastography to measure the stiffness of knee ligaments in healthy adults and in people with knee osteoarthritis. The goal is to establish normal stiffness values across different ethnic groups and to see how ligament stiffness changes after clinically indicated injection therapy. Participants will undergo ultrasound exams and clinical assessments, with follow-up for those receiving injections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Shear wave elastography (ultrasound imaging) and ultrasound-guided injection therapy (corticosteroid, hypertonic dextrose, or platelet-rich plasma)
What this could lead to
If successful, this could establish normal knee ligament stiffness values across ethnicities and reveal how these change with osteoarthritis and treatment, potentially improving diagnosis and therapy monitoring.
What could go wrong
This is an observational and exploratory study, not a treatment trial. The findings may not directly change clinical practice, and the injection therapies are given based on routine care, not as part of a controlled experiment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for KNEE OSTEOARTHRITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Taiwan University Hospital, Bei-Hu Branch

    RECRUITING

    Taipei, Taipei City, 108, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.