Which knee implant lasts longer? a Head-to-Head test

NCT ID NCT02766231

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This study follows people with knee osteoarthritis who receive one of two total knee replacement designs: a cruciate-retaining (CR) or a posterior-stabilized (PS) implant. The goal is to compare how well each design relieves pain, restores function, and holds up over time. Researchers will track clinical scores, X-ray results, and patient-reported outcomes, as well as any complications, to see if one implant offers better long-term results.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Two types of total knee replacement prostheses: a cruciate-retaining (CR) design and a posterior-stabilized (PS) design
What this could lead to
If successful, this could help surgeons choose the best knee implant design for individual patients, improving long-term outcomes and satisfaction after knee replacement surgery.
What could go wrong
This is an observational post-market study, not a randomized controlled trial, so results may be influenced by patient selection. Outcomes depend on surgical technique and patient factors, and the study does not guarantee that one implant is superior.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Casa di cura Citta' di Parma

    Parma, Parma, 43100, Italy

  • Clinique d'Eich - centre Hospitalier de Luxembourg

    Luxembourg, Luxembourg, 1460, Luxembourg

  • Cliniques Universitaires Saint-Luc ASBL

    Brussels, Brussels Capital, 1200, Belgium

  • I.R.C.C.S. Galeazzi

    Milan, Milano, 20161, Italy

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