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Oxygen flow settings after breathing tube removal put to the test

NCT ID NCT07007715

Recruiting now Disease control Sponsor: National Taiwan University Hospital Source: ClinicalTrials.gov ↗

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This trial tests four different methods for setting the flow rate of a high-flow nasal cannula (a device that delivers warm, moist oxygen) after a breathing tube is removed. The goal is to find which approach best prevents the need for additional breathing support or re-intubation. About 480 adults who are ready to have their breathing tube removed will be randomly assigned to one of four flow-setting strategies: a fixed low flow, a fixed high flow, or one of two methods that tailor the flow to the patient's breathing or oxygen levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
high-flow nasal cannula oxygen therapy with different flow-setting strategies
What this could lead to
If successful, this could establish a standard, evidence-based method for setting oxygen flow after breathing-tube removal, potentially reducing the need for further breathing support.
What could go wrong
This is a single-center trial testing different flow-setting strategies, not a new drug or device. The best approach may still fail to improve outcomes, and results may not apply to all hospitals or patient types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EXTUBATION READINESS RESPIRATORY FAILURE WITH HYPOXIA

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Taiwan University Hospital

    RECRUITING

    Taipei, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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