Can a sound wave calm addiction? ultrasound targets the Brain's craving center

NCT ID NCT07734623

First seen Jul 29, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This trial tests whether a single session of low-intensity focused ultrasound aimed at a brain region linked to reward and craving can safely reduce substance cravings and prevent relapse in people with severe opioid or amphetamine use disorder. Sixty participants will receive the ultrasound treatment and be followed for up to two years to track craving levels, drug use, and mental health. The goal is to see if this non-invasive approach can help control addiction when standard treatments are not enough.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
low-intensity focused ultrasound targeting the nucleus accumbens
What this could lead to
If it works, this could offer a non-invasive brain stimulation option to help people with severe substance use disorder reduce cravings and stay off drugs.
What could go wrong
This is an early-stage trial with only 60 participants, so results may not apply broadly. The effects may be temporary, and the procedure carries unknown risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AMPHETAMINE USE DISORDER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Taiwan University Hospital

    RECRUITING

    Taipei, 100229, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.