Boosted flu shot may offer better protection for seniors

NCT ID NCT06676644

Recruiting now ⭐️ VACCINE ⭐️ Sponsor: National Taiwan University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares an adjuvanted (boosted) flu vaccine to a standard flu vaccine in 200 adults aged 65 and older who have chronic medical conditions like diabetes or heart disease. Researchers will measure immune response and safety over one year. The goal is to see if the adjuvanted vaccine provides stronger protection against influenza in this vulnerable group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: adjuvanted influenza vaccine (aIIV4) and non-adjuvanted influenza vaccine (IIV4)
What this could lead to: If the adjuvanted vaccine works better, it could lead to stronger flu protection for older adults with chronic health issues.
What could go wrong: This is a small, early-phase study (200 participants) in one country, so results may not apply to all elderly populations. The vaccines may show similar effectiveness, or the adjuvanted version could cause more side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

influenza prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ELDERLY INFLUENZA VACCINES

Contacts and locations

Locations

National Taiwan University Hospital
RECRUITING

Taipei, 100225, Taiwan

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