ELDERLY

This study compares two seasonal flu vaccines—one with an added booster (adjuvanted) and one without—in adults aged 65 and older who have at least one chronic condition like diabetes or heart disease. The goal is to see which vaccine triggers a stronger immune response and is saf…

This study looks at whether metformin, a diabetes medicine, can help improve memory and thinking in overweight or obese older adults who have mild cognitive impairment (MCI). Researchers will give metformin or a placebo to 54 people aged 60-75 for 26 weeks. They will use brain sc…

This study looks at whether it is safe to stop antibiotics early in elderly patients (65+) hospitalized with a viral infection. Many seniors get antibiotics even when they only have a virus, which can cause side effects and lead to antibiotic resistance. Researchers will compare …

This study tests whether giving elderly patients with kidney disease a personalized amount of fluids, guided by a lung water monitor, can prevent acute kidney injury after a heart procedure called coronary angiography. The trial involves 320 participants aged 60 and older with ch…

This early-stage study tests whether a combination of two experimental drugs, GI-102 and GIB-7, can improve immune function and other signs of aging in healthy adults and cancer survivors. The trial involves 15 participants who will receive either the drug combo or a placebo for …

This study looks at whether adding local muscle vibration to standard rehabilitation can help elderly patients (75+) recover muscle strength, mobility, and reduce pain after hip fracture surgery. About 25 participants will receive vibration sessions five times a week for four wee…

This study is testing a friendly AI chatbot that guides people through telling their life stories. The goal is to see if this helps improve emotional well-being, especially for older adults and people with mental health conditions living in care homes. Participants will have one …

This study looks at whether using a positive airway pressure (PAP) machine at night can improve thinking, sleepiness, and quality of life in older veterans (age 60+) who have both COPD and obstructive sleep apnea. About 668 participants will use PAP therapy and be tested on memor…

This study looks at how well the body digests and uses protein from peas in healthy young and older adults who eat either a vegetarian or omnivorous diet. Researchers want to learn if age or diet affects how much protein the body can actually use. The findings will help create be…

This study looks at why some older adults improve more with exercise than others. Researchers will track 900 people aged 60 and older as they follow different physical activity programs. The goal is to find personalized exercise plans that work best for each person to maintain mu…

This study is testing whether a team of different specialists (like surgeons, cancer doctors, and geriatricians) can create better, personalized treatment plans for older adults (ages 60-90) with lung cancer. The goal is to see if this team approach helps people live longer witho…

This study watches 1,200 elderly patients (65+) before, during, and after surgery to understand why some develop serious complications like delirium. Researchers collect blood samples and health data to build a tool that predicts these risks. The goal is to improve care and recov…

This study looks at whether certain blood markers and brain scans can help predict which older adults with memory loss and frailty will need to visit the emergency room within six months. Researchers will follow 110 participants aged 65 and older who have lost some independence. …

This study looks at the best treatment for older adults (over 60) who had a stroke caused by a common heart defect called PFO (a small hole in the heart). Researchers will compare three options: closing the hole with a device, taking blood-thinning medication, or taking antiplate…

This study looks at whether older men with prostate cancer who have been on hormone therapy for more than three years can stop taking it. The idea is that their bodies may no longer produce testosterone, making the shots unnecessary. Researchers will monitor testosterone levels t…