Umbilical cord cells could patch up painful anal fistulas
NCT ID NCT04190862
First seen Nov 18, 2025 · Last updated Jun 22, 2026 · Updated 35 times
Summary
This early-phase trial tests whether injecting special cells from human umbilical veins (E-CEL UVEC) can safely help heal simple anal fistulas after surgery. The study involves 39 adults who are already scheduled for fistulotomy. Researchers will monitor for side effects over two weeks and check if the fistula comes back at 6 and 24 weeks.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Weill Cornell Medical College - NewYork-Presbyterian Hospital
RECRUITINGNew York, New York, 10065, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
E-CEL UVEC (endothelial cells from human umbilical vein)
What this could lead to
If successful, this could lead to a new cell therapy that improves healing and reduces relapse after fistula surgery.
What could go wrong
This is a very early Phase 1 trial with only 39 people, so it is mainly checking safety, not yet proving it works. The cells may not improve healing or could cause side effects.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.