Stem cell showdown: donor vs. your own fat for Crohn's fistulas
NCT ID NCT05974280
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests two stem cell treatments for anal fistulas in people with Crohn's disease. One uses donor stem cells (Alofisel), the other uses stem cells from the patient's own fat. The goal is to see which works better at closing the fistula. The study plans to enroll 20 adults with complex anal fistulas.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
stem cells (Alofisel or fat-derived stem cells)
What this could lead to
If successful, this could point toward a more affordable and effective treatment for anal fistulas in Crohn's disease, potentially using the patient's own fat cells.
What could go wrong
This is a very small pilot study with only 20 participants, so results may not apply to everyone. The high cost and complexity of Alofisel may limit its use, and the autologous fat approach is still experimental.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CHU Nantes
RECRUITINGNantes, Nantes, 44000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••