New combo therapy aims to tackle rare skin cancer

NCT ID NCT05583708

First seen Apr 24, 2026 · Last updated May 12, 2026 · Updated 3 times

Summary

This study tests a combination of two FDA-approved drugs—pembrolizumab (an immunotherapy that helps the immune system fight cancer) and lutetium Lu 177 dotatate (a radioactive drug that kills cancer cells)—in about 18 people with Merkel cell carcinoma. The goal is to see if the pair can shrink tumors better than either alone. Participants must have somatostatin receptors on their cancer cells for the radioactive drug to work.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Iowa Hospitals and Clinics

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact Email: •••••@•••••

    Contact

  • University of Wisconsin Carbone Cancer Center

    RECRUITING

    Madison, Wisconsin, 53792, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Weill Cornell Medicine/NewYork-Presbyterian Hospital

    RECRUITING

    New York, New York, 10065, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.