Heart bypass showdown: does using more arteries save lives?

NCT ID NCT03217006

Recruiting now Disease control Sponsor: Weill Medical College of Cornell University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests whether using two or more arterial grafts during heart bypass surgery is better than using just one. About 4,300 patients will be randomly assigned to receive either a single arterial graft or multiple arterial grafts. The goal is to see if multiple grafts reduce the chance of death, stroke, heart attack, or the need for repeat procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: arterial grafts (blood vessels used in heart bypass surgery)
What this could lead to: If it works, this could show that using more arterial grafts during bypass surgery lowers the risk of death, stroke, or needing another procedure.
What could go wrong: This is a large trial, but results may not apply to older patients or those with weaker hearts. Risks include bleeding, infection, and stroke from surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder heart disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE HEART DISEASES

Contacts and locations

Locations

Allegheny General Hospital (Cardiovascular Institute)
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
Anthea Hospital
RECRUITING

Bari, Italy
Baystate Health
RECRUITING

Springfield, Massachusetts, 01109, United States
Centro Hospitalar e Universitário São João
RECRUITING

Porto, Portugal
Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44106, United States
Dedinje Cardiovascular Institute
RECRUITING

Belgrade, Serbia
Duisburg Heart Center
RECRUITING

Duisburg, Germany
Düsseldorf University
RECRUITING

Düsseldorf, Germany
Essen University
RECRUITING

Duisburg, Germany
European Hospital
RECRUITING

Rome, Italy
Federal University of Sao Paulo
RECRUITING

São Paulo, Brazil
Fondazione Poliambulanza
RECRUITING

Brescia, Italy
Fuwai Hospital
RECRUITING

Beijing, China
General University Hospital, Prague
RECRUITING

Prague, Czechia
Giessen Hospital
RECRUITING

Giessen, Germany
HDZ NRW Bad
RECRUITING

Oeynhausen, Germany
Hamilton General Hospital
RECRUITING

Hamilton, Canada
Heart Center (Herzzentrum)
RECRUITING

Leipzig, Germany
Hospital Clinic de Barcelona (ICCV)
RECRUITING

Barcelona, Spain
Hospital Univeritario Del Vinalopo
RECRUITING

Alicante, Spain
Hospitalar de Lisboa Central
RECRUITING

Capuchos, Portugal
Icahn School of Medicine, Mount Sinai
RECRUITING

New York, New York, 10029, United States
Innsbruck (Medical University) Austria
RECRUITING

Innsbruck, Austria
Jena University Hospital
RECRUITING

Jena, Germany
Jilin Heart Hospital
RECRUITING

Changchun, China
Krankenhaus Nord Vienna North Hospital
RECRUITING

Vienna, Austria
Krankenhaus der Barmherzigen Brüder Trier
RECRUITING

Trier, Germany
Lenox Hill Hospital (Northwell)
RECRUITING

New York, New York, 10075, United States
London Health Sciences Ontario Canada
RECRUITING

London, Canada
MU Vienna Austria
RECRUITING

Vienna, Austria
MUMC Maastricht (University Medical Centre)
RECRUITING

Maastricht, Netherlands
Maria Cecilia Hospital GVM
RECRUITING

Cotignola, Italy
Medical University of Silesia (Katowice)
RECRUITING

Katowice, Poland
National Taiwan University Hospital
RECRUITING

Taiwan, China
National University of Singapore
RECRUITING

Singapore, Singapore
Nebraska Heart Hospital
RECRUITING

Lincoln, Nebraska, 68526, United States
NewYork-Presbyterian Brooklyn Methodist Hospital
RECRUITING

Brooklyn, New York, 11215, United States
NewYork-Presbyterian Queens
RECRUITING

New York, New York, 11355, United States
Ospedale Le Molinette
RECRUITING

Torino, Italy
Robert-Bosch-Hospital
RECRUITING

Stuttgart, Germany
Royal Victoria Hospital (McGill)
RECRUITING

Québec, Canada
Ruijin Hospital Shanghai Jiao Tong University School of Medicine
RECRUITING

Shanghai, China
Saitama Medical University
RECRUITING

Saitama, Japan
Severance Cardiovascular Hospital, Yonsei University College of Medicine
RECRUITING

Sinchŏn-dong, South Korea
St. Boniface General Hospital / WHRA
RECRUITING

Winnipeg, Canada
Sunnybrook Health Sciences Centre
RECRUITING

Toronto, Canada
Teda Hospital (TICH)
RECRUITING

Tianjin, China
Toronto General Hospital
RECRUITING

Toronto, Canada
Universita' Cattolica del Sacro Cuore
RECRUITING

Roma, Italy
Universite Laval Quebec (CRIUCPQ) Canada
RECRUITING

Québec, Canada
University Hospital (Praceta Mota Pinto)
RECRUITING

Coimbra, Portugal
University Hospital Dubrava
RECRUITING

Zagreb, Croatia
University Hospital Erlangen
RECRUITING

Erlangen, Germany
University Hospital of Montreal (CHUM)
RECRUITING

Montreal, Canada
University Medical Center of Goettingen
ENROLLING_BY_INVITATION

Göttingen, Germany
University of Colorado
RECRUITING

Boulder, Colorado, 80309, United States
University of Nebraska Medical Center
RECRUITING

Omaha, Nebraska, 68198, United States
University of Ottawa Heart Institute Canada
RECRUITING

Ottawa, Canada
Weil Cornell Medical College Department of Cardiothoracic Surgery
RECRUITING

New York, New York, 10065, United States

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