Weill Medical College Of Cornell University

This phase 3 trial tests whether injecting a concentrate of your own bone marrow (BMAC) into the jaw joint during arthroscopy reduces pain and damage better than a standard steroid shot. Twenty adults with long-lasting TMJ pain will be randomly assigned to one of the two treatmen…

This study tests whether adding a bone-marrow concentrate injection during routine back surgery helps the spinal disc heal better. About 90 adults with a herniated disc will get either surgery alone or surgery plus the injection. Researchers will use MRI scans and pain questionna…

This study tests an immunotherapy called PDS0101 in 27 adults with both HIV and HPV 16. The goal is to see if it is safe and can strengthen the immune system's response against HPV, which can cause cancers like anal and cervical cancer. All participants will receive three doses o…

This study will compare two types of PET scans (using different radioactive tracers) in 6 adults with suspected meningioma who are scheduled for surgery. Each person will get both scans at least 24 hours apart. The goal is to see which tracer gives clearer images of the tumor, wh…

This study tests a mobile app called Maya that teaches cognitive behavioral therapy skills to adults who recently had a stroke and feel depressed or anxious. Ten participants will use the app for a few weeks to see if it is easy to use and helps improve their mood. The goal is to…

This pilot study tests whether using bright light therapy for an hour each morning, delivered through an iPad app, is tolerable for people with advanced melanoma or non-small cell lung cancer who are about to start immunotherapy. The idea is that synchronizing the body's internal…

This study investigates whether a single session of whole-body hyperthermia (using an infrared sauna) can quickly improve symptoms of depression and anxiety. Researchers will measure brain activity, inflammation, and mood changes in four groups: healthy postpartum women, postpart…

This study tests whether a mobile app called Attuned can help transgender and gender diverse people modify their voice as well as standard in-person therapy. Fifty participants will either use the app for 11 weeks or attend in-person sessions. Researchers will measure voice quali…

This study tests a new device that uses muscle signals from the face and neck to recognize silent speech and turn it into voice. It is for adults who have lost their voice due to laryngectomy or severe voice problems. The goal is to see if the device can accurately identify words…

This study compares custom-length ureteral stents (based on each person's imaging) to standard one-size-fits-all stents in 128 adults having kidney stone surgery. The goal is to see if the custom stents reduce pain, urinary issues, and other symptoms. Participants will fill out a…

This study tests whether listening to calming music during a nail biopsy can lower pain and anxiety. About 30 adults will be randomly assigned to hear a playlist or get standard care. After the procedure, they will rate their pain, anxiety, and satisfaction. The goal is to see if…

This study tests a device called TUNES, which delivers gentle electrical stimulation through a menstrual disc to nerves near the uterus. The goal is to see if it can reduce pain and the need for pain medication in 60 women after uterine fibroid embolization. Participants will be …

This study will test whether adding a mental health app called TREE-Connect to remote therapy sessions helps reduce depression in adults aged 50 to 80. Sixty participants with mild-to-moderate depression will use the app and attend therapy remotely. The main goal is to see if peo…

This pilot study will test whether using ultrasound during common office procedures for voice and swallowing problems is helpful and practical. Researchers will enroll 200 adults with conditions like chronic cough, vocal cord issues, or swallowing difficulties. They will measure …

This study looks at whether a virtual reality (VR) program called CAST can help older adults with mild cognitive impairment (mild memory problems) stay socially and mentally engaged. Researchers will test how easy and enjoyable the VR system is for 312 people aged 65 and older. T…

This study is developing and testing an intelligent software system designed to provide cognitive and social support to older adults with mild cognitive impairment (MCI). The software adapts to each user's abilities and needs. Researchers will enroll 290 participants aged 62 and …

This study is testing whether functional MRI brain scans can predict and track how well children and teens with obsessive-compulsive disorder (OCD) respond to a type of therapy called Exposure and Response Prevention (ERP). Thirty participants aged 10 to 17 will receive 14 weekly…

This study tests a computer tool that uses artificial intelligence to alert doctors when a pregnant patient may be at high risk for postpartum depression. The tool gives doctors a risk score and suggests steps like referrals or educational materials. Researchers will ask 160 preg…

This study aims to develop and test digital assistant tools that help older adults, including those with mild cognitive impairment (MCI), manage healthcare tasks like finding services, handling medical bills, and using Medicare.gov. Researchers will interview 600 participants to …

This study is developing and testing a screening tool for primary care doctors to spot signs of neglect in older adults with dementia, along with a mobile app called SIRENS that provides caregivers with expert-reviewed information and goal-setting features. The current phase will…