Weill Medical College Of Cornell University

This study tests whether screening for elder neglect in primary care, combined with a caregiver support app, can reduce neglect in older adults with dementia. Researchers will compare three groups: one receiving screening alone, one receiving screening plus the SIRENS app, and on…

This trial tests whether a one-time injection of a person's own concentrated fat can reduce pain and improve function in adults with chronic tendinopathy—tendon pain lasting more than three months that hasn't improved with usual treatments. Participants undergo a same-day procedu…

This trial tests whether adding a small dose of total body radiation to standard CAR T-cell therapy can help the immune cells grow stronger and last longer in the body. It enrolls adults with relapsed or hard-to-treat diffuse large B-cell lymphoma or multiple myeloma who are alre…

This study tests whether brain imaging and clinical data can help select the best treatment for people with depression that hasn't improved with standard therapies. Participants receive either repetitive transcranial magnetic stimulation (rTMS) or ketamine, and researchers check …

This study tests an immunotherapy called PDS0101 in 27 adults with both HIV and HPV 16. The goal is to see if it is safe and can strengthen the immune system's response against HPV, which can cause cancers like anal and cervical cancer. All participants will receive three doses o…

This study is looking at whether a blood test called Galleri can help detect ovarian cancer early in people with BRCA1 or BRCA2 gene changes, who are at higher risk. Participants will give a blood sample and answer questionnaires about their experience. The study will also check …

This study will compare two types of PET scans (using different radioactive tracers) in 6 adults with suspected meningioma who are scheduled for surgery. Each person will get both scans at least 24 hours apart. The goal is to see which tracer gives clearer images of the tumor, wh…

This trial tests whether Gocovri, an extended-release form of amantadine, can reduce disability and improve cognitive function in adults who have brain damage from radiation therapy. Participants take the drug daily for about 24 weeks, with the dose increasing after the first mon…

This study compares custom-length ureteral stents (based on each person's imaging) to standard one-size-fits-all stents in 128 adults having kidney stone surgery. The goal is to see if the custom stents reduce pain, urinary issues, and other symptoms. Participants will fill out a…

This trial compares using a lower gas pressure (8 mmHg) with the AirSeal device versus standard pressure (15 mmHg) during robotic weight-loss surgery. The goal is to see if lower pressure helps patients feel less pain and leave the recovery room sooner. Adults aged 18 and older h…

This study tests whether a non-invasive brain stimulation technique called rTMS can improve depression in people with bipolar disorder. Researchers use brain scans to create a personalized map for each participant, targeting the exact brain circuits involved in mood shifts. Parti…

This study tests a mobile app called Maya that teaches cognitive behavioral therapy skills to adults who recently had a stroke and feel depressed or anxious. Ten participants will use the app for a few weeks to see if it is easy to use and helps improve their mood. The goal is to…

This pilot study tests whether using bright light therapy for an hour each morning, delivered through an iPad app, is tolerable for people with advanced melanoma or non-small cell lung cancer who are about to start immunotherapy. The idea is that synchronizing the body's internal…

This study investigates whether a single session of whole-body hyperthermia (using an infrared sauna) can quickly improve symptoms of depression and anxiety. Researchers will measure brain activity, inflammation, and mood changes in four groups: healthy postpartum women, postpart…

This study tests whether a mobile app called Attuned can help transgender and gender diverse people modify their voice as well as standard in-person therapy. Fifty participants will either use the app for 11 weeks or attend in-person sessions. Researchers will measure voice quali…

This study tests a new device that uses muscle signals from the face and neck to recognize silent speech and turn it into voice. It is for adults who have lost their voice due to laryngectomy or severe voice problems. The goal is to see if the device can accurately identify words…

This study tests a device called TUNES, which delivers gentle electrical stimulation through a menstrual disc to nerves near the uterus. The goal is to see if it can reduce pain and the need for pain medication in 60 women after uterine fibroid embolization. Participants will be …

This study will test whether adding a mental health app called TREE-Connect to remote therapy sessions helps reduce depression in adults aged 50 to 80. Sixty participants with mild-to-moderate depression will use the app and attend therapy remotely. The main goal is to see if peo…

This trial tests whether injecting local anesthetic into different layers of the skin on the forearm changes how long the numbing effect lasts. Healthy adults receive a small injection of lidocaine with epinephrine either just under the skin or into the skin itself. Researchers m…

This pilot study will test whether using ultrasound during common office procedures for voice and swallowing problems is helpful and practical. Researchers will enroll 200 adults with conditions like chronic cough, vocal cord issues, or swallowing difficulties. They will measure …

This study looks at whether a virtual reality (VR) program called CAST can help older adults with mild cognitive impairment (mild memory problems) stay socially and mentally engaged. Researchers will test how easy and enjoyable the VR system is for 312 people aged 65 and older. T…

This study is developing and testing an intelligent software system designed to provide cognitive and social support to older adults with mild cognitive impairment (MCI). The software adapts to each user's abilities and needs. Researchers will enroll 290 participants aged 62 and …

This study is developing and testing a screening tool for primary care doctors to spot signs of neglect in older adults with dementia, along with a mobile app called SIRENS that provides caregivers with expert-reviewed information and goal-setting features. The current phase will…