Brain scans may predict OCD therapy success in children

NCT ID NCT07570108

First seen Jun 25, 2026 · Last updated Aug 06, 2026 · Updated 3 times

Summary

This study is testing whether functional MRI brain scans can predict and track how well children and teens with obsessive-compulsive disorder (OCD) respond to a type of therapy called Exposure and Response Prevention (ERP). Thirty participants aged 10 to 17 will receive 14 weekly ERP sessions, followed by booster sessions. They will undergo brain scans and symptom assessments before, during, and after therapy to see if brain connection patterns relate to symptom changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Exposure and Response Prevention (ERP) therapy
What this could lead to
If successful, this could help doctors predict which children with OCD will benefit most from ERP therapy, personalizing treatment and saving time.
What could go wrong
This is a small, early-stage study with only 30 participants and no comparison group. The brain scan findings may not reliably predict therapy outcomes in larger, more diverse groups.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • NewYork-Presbyterian Hospital / Weill Cornell Medicine

    New York, New York, 10065, United States

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