Can a single ketamine infusion quiet the obsessive mind?
NCT ID NCT02624596
First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This study tests whether a single low dose of ketamine can quickly reduce obsessive-compulsive disorder (OCD) symptoms. Adults with OCD will receive either ketamine or a comparison drug, and researchers will measure symptom changes using a standard OCD scale. The trial also uses brain imaging to explore how ketamine affects brain chemistry, aiming to understand why it might work.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ketamine (a single intravenous infusion)
- What this could lead to
- If successful, this could point toward a fast-acting treatment for OCD and reveal brain mechanisms behind symptom relief.
- What could go wrong
- This is a phase 2 trial with a single dose, so effects may be short-lived or not work for everyone. Ketamine can cause temporary side effects like dissociation or nausea.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Stanford University
Stanford, California, 94305, United States
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