Stanford University

This phase 1 trial tests whether giving a bone marrow infusion along with a deceased donor kidney transplant can help the body accept the new kidney without needing lifelong anti-rejection drugs. The study enrolls adults with end-stage kidney disease who are already listed for a …

This study tests whether a special treatment before a kidney transplant can help the body accept the new organ without needing lifelong anti-rejection drugs. Participants receive radiation and immune-suppressing drugs, followed by an infusion of donor stem cells and the patient's…

This trial tests whether combining the drug mogamulizumab with low-dose total skin electron beam therapy works better than either alone for people with mycosis fungoides or Sezary syndrome, two rare types of skin lymphoma. Participants receive both treatments over several weeks. …

This study tests whether giving three drugs (gemcitabine, docetaxel, and toripalimab) before standard radiation can safely improve outcomes for people with a specific throat cancer caused by the Epstein-Barr virus. About 24 adults with advanced but not spread cancer will receive …

This early-phase trial tests a cell therapy called Orca-T combined with standard drugs to prevent graft-versus-host disease (GVHD) in 24 adults with advanced blood cancers (like leukemia or MDS) receiving stem cell transplants from partially matched donors. The main goal is to se…

This study tests whether meals designed for South Asian and Filipino cultures, following diabetes guidelines, can improve blood sugar control in people with type 2 diabetes. Thirty participants will wear a continuous glucose monitor for a month while eating their usual diet and t…

This study compares a shorter course of brachytherapy (3 sessions) to the standard 4-session regimen for locally advanced cervical cancer. About 41 participants will receive either 3 or 4 high-dose radiation treatments based on what is feasible for them. The goal is to see if the…

This study tests whether dipyridamole, a drug usually used for heart conditions, can raise low phosphate levels in kidney transplant recipients. Researchers will give the drug to 90 adult patients when their phosphate drops below normal. The goal is to see if it improves phosphat…

This study tests whether a 5-day course of radiation before surgery is as safe and effective as the standard 25-day course for adults with soft tissue sarcoma. Researchers will track complication rates and whether the cancer comes back. The goal is to make treatment faster and mo…

This phase 2 trial is testing a combination of three immune-boosting drugs (relatlimab, nivolumab, and ipilimumab) in 60 people with melanoma that has spread to the brain. The study includes both patients with and without symptoms from their brain tumors. The main goal is to see …

This study tests whether deep transcranial magnetic stimulation (TMS) can help Veterans with alcohol use disorder reduce relapse. About 100 participants will receive TMS targeting brain circuits linked to craving and emotional processing. The goal is to increase alcohol-free days…

Stanford University is studying whether the drug pramipexole can help people with depression, and if its effects depend on specific brain circuits. Sixty adults with recent depressive symptoms will take pramipexole for 8 weeks, then taper off over 2 weeks. The study uses brain im…

This early-phase trial is testing a new type of immunotherapy called B7-H3 CAR T cells in children and young adults whose solid tumors (such as neuroblastoma, sarcoma, or osteosarcoma) have come back or not responded to standard treatments. The therapy involves taking a patient's…

This study compares two surgical approaches for Fuchs endothelial dystrophy, a condition that clouds the cornea. One is a full corneal transplant (DMEK), the other is a simpler procedure that removes only the diseased cells (DSO) plus Ripasudil eye drops to help healing. 60 parti…

This study tests whether counseling plus a muscle relaxant (tizanidine) can help adults who have used opioids for a long time reduce their pain medication after elective surgery. About 375 participants will be randomly assigned to one of three groups: the combo treatment, counsel…

This large study tests a new way of managing type 2 diabetes in community health centers. The approach uses a team of providers and technology to personalize care. Researchers will compare blood sugar control in clinics that start the program at different times. The goal is to se…

Stanford University is testing the da Vinci Xi robot for various surgeries in children aged 6-21. The study will enroll 250 participants to check if the robot is safe and works well. The goal is to see if robotic surgery can be a good option for kids needing procedures like gallb…

This study tests an adaptive web-based program called Partners Connect for military couples. It aims to reduce drinking in concerned partners and encourage service members to seek help for alcohol use. About 744 couples will participate, comparing the online program to standard w…

This study tests a smart system that uses facial expressions to adjust computerized brain training in real time, aiming to keep older adults engaged and motivated. Researchers will enroll 80 people aged 60-89 with mild cognitive concerns. The goal is to see if this personalized a…

This study looks at whether adding two extra treatments—neuromuscular electrical stimulation (NMES) and blood flow restriction (BFR)—to standard physical therapy can help teens recover better after ACL reconstruction. Forty adolescents who had ACL surgery will be assigned to eith…

This study looks at how fat cells work differently in normal-weight people with type 2 diabetes compared to those without diabetes. Researchers will test two drugs, pioglitazone and tirzepatide, to see if they improve insulin resistance and fat storage. About 104 adults aged 30-7…

This phase 2 trial tests whether a gene therapy gel called BVEC can reduce the return of squamous cell carcinoma (a type of skin cancer) in people with recessive dystrophic epidermolysis bullosa (RDEB), a rare genetic condition that causes fragile, blistering skin. The gel is app…

This study tests a combination of the targeted drug tagraxofusp with two chemotherapy drugs (cladribine and cytarabine) in 20 adults whose acute myeloid leukemia (AML) has come back or not responded to prior treatment. The goal is to find the safest dose and see how well the comb…

This early-stage trial tests a new treatment for adults with a returning, aggressive brain cancer called glioblastoma. The therapy uses the patient's own immune cells, modified to recognize and attack the cancer, and delivers them directly into the brain. The main goals are to se…

This phase 1 trial tests a personalized, accelerated radiation therapy for locally advanced lung cancer. The radiation dose is tailored to each patient's tumor size and location, aiming to deliver a higher dose in fewer sessions. The study will enroll 45 adults with non-small cel…

This study tests whether a daily ergothioneine supplement can replenish low levels of this nutrient in people with kidney failure who are on dialysis. Dialysis removes waste but also strips away beneficial chemicals like ergothioneine. Researchers will give 28 participants either…

This study compares standard surgery alone versus a short course of radiotherapy followed by surgery for women with ductal carcinoma in situ (DCIS), a very early form of breast cancer. The goal is to see if pre-surgery radiation can completely eliminate the cancer cells in the re…

This study tests whether a nutrition program that provides twice-daily meal delivery for up to 90 days after hospital discharge, plus diet education, can reduce food insecurity in people with type 1 or type 2 diabetes. About 160 hospitalized patients who screen positive for food …

This study compares three approaches to help pregnant women and new mothers maintain a healthy weight. About 795 participants will receive either self-management support via mobile app or mail, community-based help from health workers, or usual care. The goal is to see which meth…

This study tests whether adding a special scaffold called BioBrace to the standard stitch repair of a shoulder muscle (subscapularis) during total shoulder replacement leads to better healing. About 100 adults getting shoulder replacement will be randomly assigned to receive eith…

This early-stage trial tests a personalized cell therapy called KYV-101 for people with progressive forms of multiple sclerosis (MS) that are not responding to standard treatments. The therapy uses a patient's own immune cells, modified to target and destroy certain immune cells …

This early-stage trial tests whether statins, a common cholesterol medicine, can prevent strictures (narrowing) in the gut for adults with Crohn's disease. About 20 participants will take either statins or a placebo daily for 6-12 months after surgery. Researchers will check for …

This study tests whether efgartigimod, a drug that lowers certain antibodies, can reduce swelling in the tear glands, saliva glands, or pancreas of people with IgG4-related disease. Five adults will receive weekly injections for 12 weeks and have regular scans and checkups. The g…

This early-phase trial is testing a new treatment called B7-H3 CAR T cells for adults with ovarian cancer that has come back and no longer responds to platinum chemotherapy. The treatment involves taking a patient's own immune cells, modifying them in a lab to better recognize an…

This study uses a blood test to detect tiny amounts of cancer DNA left after standard treatment for early-stage non-small cell lung cancer. People whose blood shows this leftover cancer are at higher risk of the cancer coming back. The study tests whether the drug durvalumab can …

This early-phase trial tests whether giving a second type of CAR T cell therapy (targeting CD22) after the standard CD19 CAR T therapy is safe and feasible for children and young adults with relapsed or hard-to-treat B-cell leukemia. About 20 participants will receive the standar…

This study is testing a new way to deliver radiation therapy for liver cancer. Instead of multiple sessions over weeks, patients receive a single, high-dose treatment guided by real-time MRI scans. The approach aims to be more precise and convenient. The trial will enroll 62 adul…

This study tests a compact heart-lung machine called Cardiohelp in 50 children with severe heart failure. The device supports the heart for up to 30 days while kids recover or await a transplant. The trial also compares two blood thinners to see which causes fewer bleeding or clo…

This early-phase trial tests a new treatment for children and young adults with medulloblastoma or similar brain tumors that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, modified to recognize and attack tumor cells, deliv…

This early-stage trial tests whether a new immune cell therapy called GD2 CAR T cells can be safely made and given to children and adults with a rare, aggressive brain tumor called H3K27M-mutant diffuse midline glioma. The study aims to find the right dose and check for side effe…

This Phase 2 trial tests bumetanide, a diuretic used for decades, in 40 people with early Alzheimer's. Researchers want to see if it is safe and might help slow cognitive decline. The study is double-blind and placebo-controlled, meaning neither patients nor doctors know who gets…

This Stanford study tests whether injecting a man's own platelet-rich plasma (PRP) into his testicles can help produce sperm. Ten men with nonobstructive azoospermia who previously failed sperm retrieval will receive the injection. Three months later, doctors will check for sperm…

This early-phase trial tests niclosamide, a drug previously used for tapeworm infections, combined with standard chemotherapy in 16 children whose acute myeloid leukemia (AML) has returned or not responded to treatment. The main goal is to find a safe dose and check for side effe…

This study tests whether adding a special collagen thread called BioBridge to standard lymph node transfer surgery can better reduce arm swelling in people with lymphedema. About 60 adults with stage I-II arm lymphedema will be followed for 12 months to measure changes in limb vo…

This study tests whether a device called Eyetronic, which delivers mild electrical pulses through the eyes, can help people with glaucoma. Glaucoma damages the optic nerve and can lead to vision loss. The trial will compare the active device to a sham (fake) version in 30 adults …

This early-phase trial is testing whether a second infusion of the CAR T-cell therapy Axi-Cel (called Axi-Cel-2) is safe for people with high-risk large B-cell lymphoma whose cancer came back after standard CAR T treatment. About 20 adults will receive the second infusion and be …

This study tests whether deep transcranial magnetic stimulation (dTMS) can help veterans with methamphetamine use disorder. Researchers will stimulate a brain region called the insula, which is involved in cravings and decision-making. Thirty veterans will receive either real or …

This early-phase study is testing whether giving a radioactive drug called Lutathera both before and after surgery is safe for people with advanced neuroendocrine tumors that have spread to the liver or lymph nodes. The trial will enroll 10 adults whose tumors are considered remo…

This study compares magnetic resonance imaging (MRI) with standard diagnostic techniques like mammography to see which method best finds and defines breast cancer. Researchers will enroll about 500 women with suspicious breast lesions to evaluate accuracy. The goal is to improve …

This study tests a special dye that makes brain tumor cells glow during surgery. The dye is given before surgery, and a special camera helps surgeons see the glowing tumor tissue. The goal is to help surgeons remove more of the tumor while protecting healthy brain tissue. The stu…

This study tests a special dye that makes brain tumor cells glow under a camera during surgery. The goal is to help surgeons see and remove more of the tumor while sparing healthy brain tissue. About 46 adults with malignant glioma or vestibular schwannoma will receive the dye be…

This study compares whole-body MRI, PET/MR, and PET/CT scans to see which is best at finding tumors in children and young adults with solid tumors, lymphoma, or osteosarcoma. Researchers will check how many tumors each scan detects and measure their metabolic activity. The goal i…

This study tests a special dye, panitumumab-IRDye800, that attaches to lung cancer cells and makes them glow under a special camera during surgery. The goal is to help surgeons see and remove all cancer tissue more accurately. About 30 adults with lung cancer or lung metastases w…

This Stanford study is testing computer algorithms to better map the heart's electrical activity in people with atrial fibrillation (AF), a common heart rhythm disorder. Researchers will compare different methods to see which best identifies problem areas in the heart. The study …

This study tests whether giving parents educational materials and in-person feeding support helps them introduce allergenic foods like eggs to infants early and keep them in the diet. Researchers will compare two groups of 92 infants to see which approach leads to earlier and mor…

This study tests a low-risk surgical procedure called LYMPHA, done at the same time as breast cancer lymph node removal, to prevent lymphedema—a chronic, painful arm swelling. About 80 women undergoing breast cancer surgery will be randomly assigned to receive LYMPHA or standard …

This study tests whether tranexamic acid (TXA), a drug that reduces bleeding, can lower inflammation and protect joint health after an ACL tear. Fifty people aged 18-30 with a recent ACL injury will receive either TXA or a placebo around the time of surgery. The goal is to see if…

This study involves 600 adults having their first open-heart surgery. Doctors will use a temporary pacemaker to test if the heart is prone to atrial fibrillation (AFib) during the operation. Those who show risk will be randomly assigned to receive the drug amiodarone or standard …

This study tests a new device called the Blossom Smart Expander for women having breast reconstruction or augmentation. Instead of weekly needle injections to slowly stretch the skin, this device automatically fills with a tiny amount of saline over time. The goal is to see if it…

This study tests a new online therapy platform called Teleo, designed specifically for children with anxiety or mood disorders. Researchers want to see if kids are more engaged during therapy sessions on Teleo compared to standard video calls. About 156 children will take part, a…

This Stanford study tests whether people with knee osteoarthritis can learn to change how they activate their calf muscles while walking, using a vibrating feedback device. The goal is to reduce the force on the knee joint. Thirty-one participants will train on a treadmill or ove…

This study is testing a 12-week early intervention program for preschoolers (ages 2 to 5) with developmental disorders like autism or intellectual disability. The program provides 12 hours of therapy each week, either at a center or at home, aiming to improve social communication…

This study tests whether a 16-week behavioral therapy called Pivotal Response Treatment (PRT) works better when done at a center or at home for young children with autism who have language delays. Researchers will compare both groups to children receiving usual care. The goal is …

This study tests a 12-week behavioral therapy program delivered via video calls to help autistic youth (ages 4-17) cope with insistence on sameness—difficulty tolerating changes in routine. Parents are trained to support their child during weekly sessions. The goal is to see if t…

This pilot study tests whether esomeprazole (Nexium), a common stomach acid medication, can improve social communication in 25 children with autism aged 2 to 6. Over 12 weeks, kids take the drug daily, and researchers measure changes in social behavior using standard rating scale…

This study from Stanford University tests whether two breathing techniques—cyclic sighing and box breathing—can lower anxiety, compared to hypnosis or listening to an audiobook about stress. Eighty adults will practice daily for 4 weeks and have their brain activity and heart rat…

This study tests whether transcranial magnetic stimulation (TMS) can reduce pain and improve thinking, mood, and physical function in people with Complex Regional Pain Syndrome (CRPS). Forty adults with CRPS will receive either real TMS or a sham treatment for two days. Researche…

This study tests whether an online Spanish course can teach parents of young children with autism to use Pivotal Response Treatment (PRT) to boost communication and social skills. Forty Spanish-speaking families with children aged 2 to 5 will take 12 weeks of online lessons, atte…

This study compares a combination of ibuprofen and acetaminophen to the opioid oxycodone for managing pain after thumb surgery (trapeziectomy) for osteoarthritis. About 121 adults will be randomly assigned to one of the two pain regimens and tracked for 30 days. The goal is to se…

This study tests whether virtual reality (VR) can help children and young adults with cancer be more physically active while in the hospital. 40 participants aged 10-25 will try both VR-assisted physical therapy and traditional physical therapy to see which one gets them moving m…

This study tests whether using an aromatherapy inhaler (with lavender or peppermint) can help reduce distress and improve coping for patients recovering from a stem cell transplant. About 50 adult patients will use the inhaler during their hospital stay. The goal is to see if thi…

This study tests a smartphone app called Matter Neuroscience that uses neurofeedback from brain scans to help people with mild to moderate depression better understand positive emotions. Researchers will enroll 240 adults to see if the app is safe and effective at reducing depres…

This study looks at the best way to clean wounds during surgery for advanced pilonidal disease. It compares standard saline to a special solution called hypochlorous acid to see which helps wounds close faster. About 72 people having surgery for stage 3 pilonidal disease will tak…

This study tests whether adding dextromethorphan (a cough suppressant) to fluoxetine (an antidepressant) can safely reduce symptoms of obsessive-compulsive disorder (OCD) and related conditions like body dysmorphic disorder. About 60 adults in California will take the combination…

This study tests whether N-acetylcysteine (NAC), a well-tolerated nutritional supplement, can reduce restricted and repetitive behaviors in children with autism. About 144 children aged 3 to 12 will receive either NAC or a placebo for 12 weeks. Researchers will measure changes in…

This study compares two online treatments for chronic pain: an 8-week cognitive behavioral therapy program (16 hours total) and a single 2-hour pain relief skills class. Researchers want to see which works better for reducing pain intensity and interference. The study will enroll…

This study compares two approaches to supportive cancer care for nearly 3,000 adults with cancer. One group gets information through email or their health record, while the other works one-on-one with a lay health worker over 12 months. The goal is to see which model better impro…

This pilot study tests whether adding a digital insomnia treatment (CBT-I) to standard suicide-focused therapy (DBT) helps reduce suicidal thoughts and self-harm in teens aged 12-18 who are at high risk for suicide. Forty-four participants will be randomly assigned to receive eit…

This study tests whether injecting a long-lasting numbing medication (Exparel) into the side of the nose can reduce severe face and headache pain. About 15 adults with conditions like migraine or cluster headache will receive either the drug or a placebo, then switch groups. The …

This Stanford study tests how ketamine quickly reduces OCD symptoms by blocking opioid receptors with naltrexone. 150 adults with OCD who haven't responded to standard treatments will receive ketamine plus either naltrexone or a placebo. The goal is to see if the opioid system is…

This study tests two simple early treatments—writing about the experience (Written Exposure Therapy) and guided breathing exercises (Capnometry Guided Breathing)—to see if they can reduce PTSD symptoms in new mothers after a traumatic childbirth. About 70 women who recently gave …

Stanford University is testing a non-invasive device that uses pulsed radiofrequency to treat chronic nerve pain after injury. The device sends magnetic pulses through the skin to target the affected nerve. This Phase 2/3 trial will enroll 95 adults to see if the treatment reduce…

This small study from Stanford tests whether rapid, non-invasive brain stimulation can reduce the urge to hoard. Ten adults with hoarding disorder will receive the treatment and report changes in their acquiring habits. The goal is to see if this safe, outpatient procedure can ea…

This pilot study at Stanford University is testing whether giving rTMS (a non-invasive brain stimulation) in the morning or evening works better for treating insomnia. Ten adults with insomnia will receive ten sessions over two weeks. Researchers will track sleep quality and brai…

This study tests whether a proven sleep therapy (CBT-I) can improve how the brain regulates emotions, helping treat depression and anxiety. Researchers will use brain scans to see changes in emotion networks. 120 adults with insomnia and depression will participate. The goal is t…

This pilot study tests a new type of surgical drain called the Interi Manifold against the standard Jackson-Pratt drain in women having implant-based breast reconstruction after mastectomy. The new drain has multiple branches and a special suction system that may remove fluid mor…

This study tests whether diphenhydramine (Benadryl) can help children and teens with autism fall asleep faster and sleep more soundly. Twenty-six participants aged 8 to 17 will receive either Benadryl or a placebo in a crossover design, with sleep measured by brain waves and acti…

This study tests whether zolpidem, a sleep medication, can improve sleep in children and teens with autism. About 26 participants aged 8-17 will receive either the drug or a placebo for 8 weeks, then switch. The goal is to see if the drug helps them fall asleep faster and sleep m…

This study tests whether suvorexant (Belsomra) can improve sleep in teenagers with autism spectrum disorder. About 26 teens aged 13-17 will receive either the drug or a placebo in a crossover design over 8 weeks. Researchers will measure sleep quality using brain wave recordings …

This study tests whether local anesthesia with sedation works as well as general anesthesia for 1-3 level lumbar decompression surgery. Researchers will measure changes in pain and disability in 100 adults aged 40-95. The goal is to find a safer, effective alternative to general …

This pilot study looks at whether a new wheeled mobility tool helps people move around more easily after total knee replacement. About 19 adults aged 18-99 who can walk with at most a cane or crutch before surgery will use the device. Researchers will track how much they use it a…

This study tests whether taking melatonin, a natural sleep aid, can help teens aged 12-18 sleep better and recover faster after major musculoskeletal surgery (like scoliosis or hip surgery). About 45 teens will receive either a fast-dissolve melatonin pill or a placebo daily. The…

This study tests a new type of spinal cord stimulation for people with long-lasting pelvic pain that hasn't improved with other treatments. The device automatically adjusts its energy based on real-time feedback to better target pain. Ten adults will be enrolled to see if it safe…

This study tests whether guanfacine, a medication typically used for blood pressure, can improve brain network function and reduce cognitive problems in people with depression. Researchers will enroll 162 adults aged 18-60 who are currently experiencing a major depressive episode…

This study tests whether a special 5-day diet that mimics fasting can lower inflammation and improve quality of life in people with mild to moderate ulcerative colitis. Participants will follow the diet for three cycles while researchers track symptom changes. The goal is to see …

This study tests whether adding fermented foods like kimchi, sauerkraut, yogurt, and kefir to the diet can reduce inflammation and improve quality of life in people with mild to moderate ulcerative colitis. Researchers will measure changes in a stool marker of inflammation and tr…

This Stanford study tests whether having a dream while under anesthesia can reduce PTSD symptoms. In a small Phase 2 trial, 42 adults with PTSD will receive either deep sedation to trigger dreaming or light sedation without dreaming. Researchers will compare changes in PTSD sever…

This pilot study tests a 16-week telehealth program that coaches parents to help their autistic children who struggle with insistence on sameness—like needing things to stay the same or getting upset over changes. Researchers will see if parents can learn the techniques and if ch…

This pilot study tests a new 12-week group therapy program called BEAR-SI for women aged 18-75 who have experienced interpersonal trauma and currently have suicidal thoughts. The program combines psychological skills, education about trauma, and physical self-defense training. Th…

This study tests whether using a virtual reality (VR) headset can make behavioral activation therapy more effective for older adults (65+) with major depression. Thirty participants will use VR to engage in activities that boost mood, and researchers will measure changes in depre…

This study compares two LASIK techniques to see which one corrects nearsightedness and astigmatism better. 70 adults aged 22 and older with healthy eyes will have one eye treated with each method. The goal is to find out if one approach leads to sharper vision without glasses.

This study is testing whether a device that sends gentle magnetic pulses (PEMF therapy) can help reduce pain after shoulder or knee surgery. About 76 adults having these surgeries will use the device or a fake one for 10 days after their operation. Researchers will measure pain l…

This study tests whether Botox injections into the skin can reduce the number of painful attacks in people with trigeminal neuralgia, a severe facial pain condition. It includes 20 adults who have not gotten enough relief from medications or are not candidates for surgery. Partic…

This pilot study tests a non-invasive 3D-printed external device to help men with erectile dysfunction achieve satisfactory sexual intercourse. Nine men with moderate to severe ED from any cause, along with their female partners, will try the device. The goal is to see if it is s…

This study compares the Gokhale Method posture therapy to standard physical therapy for people with chronic lower back pain. Researchers want to see which approach works better for reducing pain and improving daily function. The study involves 100 adults aged 18-65 with moderate …

This study tests whether a cardiac rehabilitation program can help adults with Fontan failure walk more each day and improve their exercise ability, frailty, and quality of life. Researchers will compare the rehab group to those receiving usual care. The trial aims to enroll 50 p…

This study tests a single online class called Empowered Relief, delivered in Spanish to adults with chronic pain. The class teaches pain relief skills, and participants fill out surveys right after, at 2 weeks, and at 1 month. The goal is to see if the class is helpful and satisf…

This study tests whether a motion-capture game called Snipperfingers can make physical therapy more engaging for children aged 6-17 who are staying in the hospital. The game uses cameras to track kids' movements as they play, aiming to encourage them to stand and move during ther…

This study tests two methods of delivering local anesthetic through a nerve block catheter after surgery: a steady continuous drip or scheduled small bursts (boluses). Researchers want to see which approach reduces pain and the need for opioid painkillers. About 240 adults having…

This early-stage trial tests whether insulin eye drops are safe for people with glaucoma and other optic nerve conditions. Researchers at Stanford will give different doses of insulin drops to 52 participants for 1-2 months. The main goal is to check for side effects, but they wi…

This study tests a new extended-release version of sodium oxybate taken as a single dose at bedtime for children with narcolepsy type 1. Researchers want to see if kids prefer it over current twice-nightly options and if it is safe and convenient. About 36 children from Stanford …

This study compares injections of a patient's own processed fat tissue (MFAT) against standard steroid shots for shoulder osteoarthritis. Researchers will track pain, function, and quality of life in 48 adults aged 25-75. The goal is to see if the fat injection provides better or…

This study tests whether virtual reality (VR) field trips can improve the emotional well-being and learning of children aged 5 to 17 who are stuck in the hospital. Participants will wear a VR headset to visit famous landmarks and then do a hands-on science experiment. Researchers…

This Stanford-led study tests whether adding a peripheral nerve stimulation (PNS) device to standard medical care can reduce chronic neuropathic pain in the lower back, pelvis, or legs. About 148 adults with long-term nerve pain will be randomly assigned to either standard care a…

This study tests a simpler way for paramedics to treat seizures in children. Instead of calculating doses, paramedics will use age-based, pre-set doses of a seizure-stopping medicine given as a shot or nasal spray. The goal is to see if this approach stops seizures before the chi…

This study collects blood and tumor tissue samples from people with head and neck or lung cancers to find biological markers that indicate low oxygen levels within tumors. Low-oxygen tumors tend to be more aggressive and resistant to standard treatments like radiation and chemoth…

This early-stage study at Stanford tests whether giving magnetic brain stimulation during sleep is safe and practical for people with major depression. Fifteen adults who have not gotten better with at least one antidepressant will receive both real and fake stimulation in separa…

This Stanford study tests whether taking 2-minute activity breaks—either strength exercises or short walks—during a sedentary workday can improve health. Researchers will measure changes in blood sugar, strength, and endurance in 40 full-time employees who sit most of the day. Th…

This study from Stanford University is looking at how a 6-week math training program changes brain activity and thinking skills in children with math learning disabilities (dyscalculia). About 180 children aged 6-12 will do math problems on a tablet at home and get weekly one-on-…

This pilot study looks at whether giving dialysis on the same day as surgery is better than not giving it for people with end-stage kidney disease. About 30 participants will be randomly assigned to one of two schedules. Researchers will track safety issues like electrolyte probl…

This study follows up to 500 children and young adults (up to age 26) with B-cell leukemia or lymphoma who have received immunotherapy like Kymriah or blinatumomab. Researchers will use surveys and medical records to track survival, remission, and unmet needs. No new treatment is…

This study compares two widely used drug classes—anti-convulsants and anti-depressants—for treating chronic pain in 450 real-world patients. Unlike typical trials that exclude many patients, this one includes people with other health issues to get results that apply to more peopl…

This study tests whether an online training course can teach parents of children with autism (ages 2-5) a therapy technique called Pivotal Response Treatment. Researchers will check if parents learn the technique and if children's communication improves. 44 families will particip…

This study collects tumor and blood samples from 3,300 people at high genetic risk for breast, ovarian, and related cancers. Researchers want to learn how these cancers develop and how well treatments work. Participants include those with BRCA1/2 or other gene mutations, or a str…

This study is building a registry of people with gastric cancer, a family history of it, or a specific gene mutation (CDH1). Participants fill out online questionnaires and provide saliva, blood, or tissue samples. The goal is to learn more about what causes stomach cancer and ho…

This study uses EEG (a non-invasive brain wave test) to find patterns in the brain that might predict how chronic low back pain changes over time. Researchers will track 130 adults with chronic low back pain and healthy volunteers for up to 5 months. The goal is to develop better…

This study looks at how a single dose of N-acetylcysteine (NAC), a common supplement, changes brain chemistry in children with autism who have repetitive behaviors. Researchers will use brain scans and EEG to measure these changes. The goal is to understand why NAC might help red…

This study at Stanford University tests whether augmented reality (AR) or virtual reality (VR) goggles can help doctors perform ultrasound-guided procedures, such as nerve blocks or placing IV lines, more precisely. About 100 adults having these procedures will use the AR/VR devi…

This study uses surveys and phone interviews to learn how COVID-19 impacts people with cancer. Researchers want to understand the challenges these patients face during the pandemic. About 50 adults with cancer will take part. No treatments or medications are involved.

This study tests a web-based program for romantic partners who are worried about their loved one's drinking. Researchers will use daily surveys from both partners to build personalized feedback that helps the concerned partner communicate better and motivate change. The goal is t…

This study tests whether hearing aids with built-in sensors and artificial intelligence can assess a person's risk of falling and help them hear better in noisy environments. Researchers at Stanford University will enroll 350 adults aged 55 and older who already wear hearing aids…

This study tests a parent coaching program for parents of teens (ages 12-18) hospitalized for suicidal thoughts, suicide attempts, or self-harm. Parents receive coaching on safety planning and parenting skills, plus help connecting to follow-up care. The goal is to see if this ex…

This study aims to create a digital decision-making aid for older adults with heart failure who are considering getting an implantable cardioverter-defibrillator (ICD). The tool will help patients weigh the benefits of preventing sudden cardiac death against the downsides of the …

This Stanford study looks at how ultra-processed foods (like sugary drinks and snacks) affect brain areas involved in reward, attention, and memory in 162 teenagers aged 13-15. Participants will have brain scans while tasting and viewing different foods, and will also eat from a …

This study compares an AI platform to human experts in evaluating how well anesthesiology trainees communicate when disclosing a medical error. About 45 residents and fellows will participate in a simulated conversation, and their communication skills will be scored by both the A…

This Stanford study watches 20 young women for 28 days to see how sleep, body rhythms, and the menstrual cycle work together. Researchers track movement, heart rate, and other body signals. The goal is to learn how these cycles might affect injury risk, not to test a treatment.

This study looks at embryos that were found to have extra or missing chromosomes (aneuploidy) or a mix of normal and abnormal cells (mosaicism) during genetic testing. Researchers want to see how often these embryos lead to a healthy baby and whether the pregnancy or child has an…

This study is screening people with recessive dystrophic epidermolysis bullosa (RDEB), a rare genetic disease that causes painful blisters and open wounds from minor skin contact. Researchers at Stanford want to learn more about the disease and the patients' cells to develop new …

This study looks at how ketamine causes feelings of dissociation (feeling detached from yourself or reality). Researchers will give ketamine to 120 psychiatric inpatients and measure their dissociative symptoms using a standard scale. The goal is to understand the brain circuits …

This study aims to understand how ketamine causes dissociative symptoms—feelings of detachment from oneself or reality—in people with epilepsy. Researchers will give ketamine to 20 adults staying in Stanford's epilepsy monitoring unit and measure their dissociative experiences us…

This study tests a simple blood test (liquid biopsy) to see if it can tell which triple-negative breast cancer patients will benefit from the drug capecitabine after standard chemotherapy. About 40 adults with leftover cancer after chemo will give blood samples before and during …

This study aims to learn more about oropharyngeal carcinoma, a type of throat cancer that can be linked to HPV. Researchers will collect blood samples from 1,000 patients before treatment and at six follow-up visits, and also gather tumor tissue when available. The goal is to bet…

This study tests whether trained community health workers (called Promotores) can help Latino/a adults learn about mental health services and feel more comfortable seeking help. About 192 participants from specific San Jose zip codes will attend six educational sessions. The goal…

Stanford University is recruiting 2,500 people with possible allergies to improve how allergies are diagnosed. Researchers will study skin test responses and look at genetic and immune system factors. This study does not test any new treatment, but aims to deepen knowledge of all…

This study looks at how well the flu vaccine works in people who have had COVID-19, including those with long-term symptoms like fatigue or diabetes. Researchers will compare immune responses between 230 adults and children (ages 9-64) who had COVID-19 and those who did not. The …

This study aims to understand how repetitive brain stimulation (TMS) changes brain activity. Researchers will use special electrodes placed inside the brain (in people with epilepsy) and noninvasive recordings to track these changes. The goal is to find reliable brain markers tha…

This study tests whether a program that delivers free groceries twice a month to food-insecure families with infants (ages 6 to 18 months) is practical and well-liked. All families also get nutrition education. The goal is to see if the program can be done successfully, not yet t…

This early-phase study at Stanford University is testing whether the statin drug rosuvastatin changes bile acid levels and gut bacteria in people with primary sclerosing cholangitis (PSC), a liver disease with no cure. Researchers will enroll 15 adults with PSC and inflammatory b…

This study uses a non-invasive brain stimulation technique called TMS to see if it can change brain activity in people with schizophrenia. Researchers will measure brain waves before and after stimulation to understand how the hippocampus works in this condition. The goal is not …

This study looks at how adolescents and young adults (ages 15-29) with cancer prefer to be involved in decisions about their treatment. Researchers will use made-up scenarios to see if participants want an active, collaborative, or passive role. The goal is to better understand w…

This Stanford study looks at 200 people with persistent atrial fibrillation (AF) who are scheduled for ablation or Maze surgery. Researchers will map the heart's electrical activity to see if the size of organized areas predicts whether the procedure works. The goal is to better …

This study from Stanford University is looking at what happens inside the body when people with heart failure exercise. Researchers will measure thousands of proteins in the blood before and after a single workout, and again after a 12-week cardiac rehab program. By comparing the…

This study is testing whether giving low-income families a monthly cash gift plus support from a community health worker can improve child health, reduce poverty, and help families use services like doctor visits and food assistance. Researchers will follow 2,400 families in San …

This study looks for proteins and other markers in the blood of 2000 adults with or suspected of having cancer. The goal is to find markers that may help doctors confirm a cancer diagnosis, choose the right treatment, and predict how well a patient will respond or if the cancer w…

This Stanford study is testing new ways to measure brain activity in people with depression using transcranial magnetic stimulation (TMS). The goal is to find better markers that could make TMS treatment more effective. The study involves 145 adults with moderate-to-severe depres…

This study tests whether a short, safe ear-water stimulation (caloric vestibular stimulation) can temporarily improve insight in people with obsessive-compulsive disorder, body dysmorphic disorder, or illness anxiety. Sixteen adults with strongly held beliefs will receive the sti…

This study at Stanford University will enroll 120 children and teens with severe obesity to develop a simple index that measures how well their bodies use insulin and their overall heart and metabolic health. Participants will wear fitness trackers and continuous glucose monitors…

This pilot study tests whether a smartwatch and smartphone app can help track mood, stress, and sleep in adolescents and young adults recently diagnosed with cancer. Twenty-five participants will wear a device for 10 days and answer quick surveys. The goal is to see if this digit…

This study collects tumor tissue from people with Hodgkin's or non-Hodgkin's lymphoma to learn more about the cancer cells. It does not test any new treatment. Participants must already be scheduled for a routine procedure to remove lymph nodes. The goal is to better understand t…

This study aims to uncover the genes and proteins that drive head and neck cancer. Researchers at Stanford will analyze tissue from 500 patients undergoing surgery to better understand how the disease develops and progresses. The goal is to lay the groundwork for future diagnosti…

This study follows 800 children who have had or will have a stem cell transplant. Researchers collect health data and tissue samples over many years to understand long-term effects and improve follow-up care. The goal is to create a database that helps doctors anticipate and prev…

This study is looking at whether analyzing the DNA of a patient's tumor can help doctors pick more effective treatments. Researchers will profile tumors from 100 adults with advanced, incurable cancer to see if they can find genetic changes that match existing drugs or clinical t…

This study at Stanford University collects tissue and blood samples from 100 adults with or at high inherited risk for stomach, esophageal, or related cancers. Researchers aim to understand how genes and proteins contribute to cancer development. The study does not test any treat…

This observational study at Stanford University looks at how levels of carotenoids (natural pigments from fruits and vegetables) in the skin relate to immune aging and skin health. Researchers will measure skin carotenoids and compare them with aging markers like wrinkles, inflam…

This study follows 600 people at higher risk for stomach cancer to track precancerous changes in the stomach lining. Researchers collect tissue, blood, and saliva samples during routine endoscopies. The goal is to understand why some people's stomach changes progress to cancer wh…

This early study tests whether two modified insulins (diluted U-200 Humalog and diluted U-500 Humulin) work faster than a current rapid insulin (Lyumjev) in 20 adults with type 1 diabetes who use insulin pumps. Participants receive each insulin after a meal, and researchers measu…

This study screens up to 1,000 people with possible food allergies to see if they qualify for future clinical trials at Stanford. Participants undergo food challenges and skin tests to confirm their allergies. The goal is to build a pool of diagnosed individuals ready for upcomin…

This study from Stanford University is looking for 100 volunteers to help understand why people's blood sugar levels respond differently to the same foods. Participants will wear a continuous glucose monitor and test various meals, supplements, and short exercises. The goal is to…

This study tests a personalized mobile tool to help women with overactive bladder (OAB) start and stick with treatment. About 30 women will use the app to learn about their condition, track symptoms, and get support. The goal is to see if the tool improves bladder health knowledg…

This study is a registry that collects contact information from people of all ages who are interested in joining future clinical trials for allergies or asthma. No treatments or tests are given—it simply helps researchers find volunteers for upcoming studies. Anyone from 0 to 100…

This Stanford study is testing whether machine learning can help predict which patients with atrial fibrillation will benefit from a heart ablation procedure. Researchers will collect data from 120 people undergoing ablation and use it to train an algorithm that forecasts success…

This study looks at whether brain scans can predict which young children with autism (ages 2 to 4) will improve their language skills after 16 weeks of Pivotal Response Treatment (PRT), a behavioral therapy. About 36 children will be randomly assigned to receive PRT right away or…

This study looks at cells and molecules collected from a gentle uterine wash during gynecologic surgery. Researchers aim to understand what types of cells are present and what they reveal about uterine health. Up to 50 participants will provide samples, which will be analyzed for…

This study is collecting medical information from 2000 people with advanced mycosis fungoides or Sézary syndrome, two rare types of skin lymphoma. The goal is to create a tool that helps doctors predict which patients are at higher or lower risk, so they can tailor treatments mor…

This study is a registry that follows up to 5,000 adults who have an IVC filter placed or removed. An IVC filter is a small device placed in a large vein to prevent blood clots from traveling to the lungs. The goal is to collect data on how well the filter works and any complicat…