Stanford University

This study tests whether a rapid form of brain stimulation, called accelerated intermittent theta-burst stimulation (aiTBS), can relieve depression in people with bipolar II disorder whose depression has not responded to other treatments. Participants receive either real or sham …

This trial investigates a new type of immunotherapy called CAR T-cell therapy that targets two proteins, CD19 and CD22, found on B-cell leukemia cells. The therapy is given along with chemotherapy to children and young adults whose leukemia has come back or has not responded to s…

This phase 2 trial tests a drug called VK-2019 in 13 patients with Epstein-Barr virus (EBV)-positive nasopharyngeal cancer that has returned or spread and has no standard treatment. VK-2019 works by blocking a key viral protein, EBNA1, which the virus needs to survive. The main g…

This study tests a text-message program called ASPIRE that sends brief coaching messages on Thursdays and Sundays to help young adults ages 18–25 who are not in college reduce their drinking. Participants must have had at least two heavy drinking days in the past month. The progr…

This early-phase trial tests whether adding immune cells—either the patient's own regulatory T cells or donor bone marrow cells—to a standard islet transplant can improve blood sugar control in people with brittle type 1 diabetes. About 24 adults aged 18 to 70 will receive one of…

This early-phase study tests a stem cell transplant method for people with advanced blood cancers like leukemia. Instead of using strong drugs to prevent complications, doctors give specially selected immune cells (regulatory T-cells) along with regular T-cells to help the body a…

This study compares two types of corneal transplant surgery (UT-DSAEK and DMEK) in 160 people with Fuchs dystrophy, a condition that clouds the cornea. It also tests whether a drug called rho-kinase inhibitor can reduce loss of important eye cells after surgery. The goal is to fi…

This study looks at whether remotely monitoring continuous glucose monitor (CGM) data can improve diabetes management in children within the first year after diagnosis. About 100 kids and teens newly diagnosed with type 1 diabetes will have their CGM data shared with their care t…

This study was designed to compare two ways to treat walled-off necrosis (a pocket of dead tissue) caused by severe pancreatitis. One method uses a scope through the mouth to clean out the pocket, the other uses surgery through the stomach. The goal was to see which approach work…

This study compares giving a single dose of antibiotics during rhinoplasty (nose surgery) versus a full course of antibiotics after surgery. The goal is to see if the single dose works just as well at preventing infections. Over 800 adults having nose surgery will take part, and …

This study tests whether long-term, mild electrical stimulation using a home device can safely slow vision loss in people with open-angle glaucoma. About 45 adults with moderate vision damage will use the device regularly. The goal is to see if this approach can protect the optic…

This study tests whether advanced CT imaging can help doctors plan better coronary bypass surgery for 200 people with heart disease. Participants get a CT scan before and after surgery to measure blood flow changes. The goal is to improve surgical decisions and reduce chest pain,…

This Phase 2 trial tests the immunotherapy drug pembrolizumab (Keytruda) in 12 people with advanced anaplastic thyroid cancer, a rare and fast-growing cancer with no standard cure. Participants receive the drug every three weeks to see if tumors shrink or stop growing. The study …

This study tests a type of radiation called high-dose brachytherapy for men with prostate cancer that hasn't spread. Doctors place tiny radioactive sources directly into the prostate to deliver a strong dose to the tumor while sparing nearby healthy tissue. The goal is to control…

This study tests whether offering financial rewards can help people with schizophrenia, bipolar disorder, or substance use disorder stick to their long-acting injectable medication after being forced into the hospital. About 1,000 participants will be randomly assigned to receive…

This study is testing whether shorter, more focused radiation treatments after lumpectomy are as safe and effective as the standard six-and-a-half-week course. About 121 women with early-stage breast cancer are receiving one of several accelerated radiation methods, including a s…

This study looks at whether a special program that uses smartphones and community feedback can help older women who are not very active to walk more. About 232 women from across the U.S. will take part. The goal is to see if this approach, combined with basic activity tips, works…

This study follows 1,500 patients with multivessel coronary artery disease who were randomly assigned to receive either coronary stenting guided by fractional flow reserve or coronary bypass surgery. Researchers will compare survival, quality of life, and chest pain relief over 1…

This study tests a drug called QBS72S in 21 adults with breast or lung cancer that has spread to the brain. The drug is given once a month through an IV. The main goal is to see if it shrinks brain tumors. The trial is active but not recruiting new participants.

This early-stage study tests a treatment that uses a patient's own immune cells, modified to recognize and attack cancer cells, for adults with B-cell blood cancers that have returned or not responded to standard therapy. The treatment is given with chemotherapy and sometimes an …

This study tests a special nail made from a fiber-reinforced material that integrates with bone over time, instead of staying in the body like metal. Ten people with knee fractures will get the implant and be followed for up to two years. The goal is to see if it reduces pain and…

This phase 2 trial tests a small implant (NT-501) placed inside the eye to protect nerve cells and slow vision loss in people with glaucoma. 54 participants will either get the implant or a sham surgery, and their vision will be tracked for 2 years. The implant releases a protein…

This phase 2 trial tests whether an implant placed in the eye can slow vision loss in people with glaucoma. The implant releases a protein that may protect nerve cells. Thirty participants will receive either the real implant or a sham procedure and be followed for two years.

This study tests whether a nerve block in the neck can increase blood flow to the brain in people who develop narrowed blood vessels after a bleeding stroke. Ten adults in the ICU will receive the block, and researchers will measure changes in blood flow and neurological function…

This early-phase trial tests whether adding pulses of the cancer drug dasatinib to standard CAR T-cell therapy (brexucabtagene autoleucel) is feasible and safe for adults with relapsed or refractory B-cell acute lymphoblastic leukemia. Eight participants receive dasatinib on a we…

This early-stage trial tests whether giving specially engineered donor immune cells (CAR T cells) along with a special stem cell transplant (Orca-T) is safe for adults with a high-risk type of leukemia called B-cell ALL. The approach is designed to help the donor cells attack the…

This study tests a 3D body scanner called NSite to see if it can reliably monitor scoliosis in teenagers. Thirteen teens with scoliosis will be scanned by three different users to check if the results are consistent. If it works, this device could offer a radiation-free way to tr…

This study explores whether special ultrasound techniques can detect early signs that cancer immunotherapy is working. Researchers will scan tumors in 30 adults with solid tumors before and after three weeks of treatment. The goal is to see if changes in blood flow measured by ul…

Stanford University is developing a mobile app that uses video of a simple physical test (the Short Physical Performance Battery) to assess physical and cognitive function in older adults. The study will collect video data from 30 healthy volunteers to train the app's AI. The goa…

This pilot study tests a radioactive imaging agent called 111In-panitumumab in 28 people with head and neck cancer. The goal is to see if it can safely and accurately find cancer in lymph nodes compared to the standard dye method used during surgery. The study is currently suspen…

This early-stage study is testing a radioactive imaging agent called [18F]-C-SNAT4 to see how it travels through the body and whether it can help detect lung cancer on PET scans. About 20 healthy volunteers and people with lung cancer will receive the tracer and undergo scans. Th…

This study tests whether replacing dirt floors with concrete in rural Bangladeshi homes can reduce infections in children. About 800 pregnant women and their future babies will take part, with children checked for parasites and diarrhea up to age 2. If concrete floors lower infec…

This study planned to use online tools like ads and social media to encourage safer sun habits and reduce skin cancer risk. It was designed for men aged 18-65 who use Facebook and are interested in LGBT topics. However, the study was withdrawn before any participants were enrolle…

This study tests a free online program called Healthy Futures: Alternative-to-Suspension, designed to teach high school students about the risks of tobacco and nicotine and provide resources to quit. About 2,540 students from schools that agree to use the program or continue thei…

This study tests whether a saphenous nerve block can safely reduce pain after surgery for a tibial plateau fracture. Typically, nerve blocks are avoided in these fractures because numbness might mask compartment syndrome, a serious complication. The saphenous nerve block targets …

This study compares two ways of asking about pain after ACL surgery: a simple 'tolerable or intolerable' question versus the standard 0-to-10 scale. The goal is to see if the simpler scale helps patients use fewer opioid painkillers during their two-week recovery. About 130 adult…

This study tests a digital program called MINDSET designed to help newly diagnosed cancer patients cope better with treatment. 440 participants will use either the program or a control, and complete questionnaires and blood tests. The goal is to see if the program improves physic…

This pilot study is testing whether giving people non-alcoholic beer or sparkling water can help them reduce their alcohol intake. 60 adults with alcohol use disorder who are already in treatment will receive one of the two drinks for 6 weeks. The main goal is to see if people fi…

This study tested whether listening to spatial audio (a type of immersive sound) could help people tolerate heat pain better. Healthy adults would have a heat device placed on their hand and rate their pain with and without the audio. The study was withdrawn before any participan…

This study compares two types of spinal cord stimulation—high frequency and burst—for treating chronic back and leg pain. Seven adults who are candidates for spinal cord stimulation will be randomly assigned to one waveform and tracked for at least 36 months. The goal is to see w…

This study tests whether a physical activity program can help pregnant people with symptoms of depression or anxiety feel better. 88 participants will be given a step goal and wear an activity tracker. The program includes weekly reminders and motivational coaching every two week…

This study looks at whether N-acetylcysteine (NAC), a well-tolerated nutritional supplement, can reduce restricted and repetitive behaviors in children with autism spectrum disorder. About 144 children who previously took part in related NAC trials will receive the supplement and…

This study aimed to compare two ways to manage pain from broken ribs: a continuous IV drip of lidocaine versus a nerve block called an erector spinae plane (ESP) block. The goal was to see which method reduces pain and improves breathing better. However, the study was withdrawn b…

This study tests whether a special silicone dressing (Neodyne embrace) can improve the appearance of abdominal scars in women who had breast reconstruction using tissue from their belly. Thirty women will have part of their incision treated with the dressing and the other part le…

This study tests a prescription cream (clascoterone) to treat acne caused by testosterone therapy in transgender men. About 18 participants will use the cream daily for 3 months to see if it reduces pimples without affecting their hormone levels. The goal is to provide a safe acn…

This study planned to test whether an augmented reality (AR) app called Reia could help stroke survivors with arm weakness do rehab exercises at home. Participants would have used an AR headset for daily 30-minute sessions over 8 weeks, with weekly video check-ins from a therapis…

This study is testing a new device that uses gentle vibrations on the belly, back, or temples to help people with chronic pain conditions like pelvic pain, abdominal pain, low back pain, or migraine. About 50 adults will try the real device or a placebo to see if it safely reduce…

This study aimed to see if having a parent appear on a video call during anesthesia induction could reduce children's anxiety as effectively as the sedative midazolam. It was designed for children aged 4 to 8 undergoing outpatient surgery. However, the study was withdrawn before …

This study tests whether an audio-visual system called AVATAR can help children aged 3 to 10 stay still during radiotherapy without needing anesthesia. The system uses calming sounds and images to distract and relax the child. If it works, it could reduce the risks and stress ass…

This study tests whether virtual reality (VR) therapy can reduce depressive symptoms in pregnant women who are hospitalized for at least three weeks. Participants will either receive VR-based behavioral activation therapy or standard social work consultations. The goal is to see …

This study aimed to see if adding nitrous oxide (laughing gas) to standard sedation during GI endoscopy (like colonoscopy) could reduce side effects such as fatigue, mental fogginess, and nausea after the procedure. The study was designed for adults 18 and older undergoing these …

This pilot study at Stanford tests whether a one-time pain relief skills session (Empowered Relief) plus educational videos on sleep, mental health, and other topics can improve overall recovery 12 weeks after a cesarean delivery. The study will enroll 60 women scheduled for a C-…

This study tests whether a live, online exercise program can improve physical function in adults waiting for a kidney transplant. Eighty participants will either join twice-weekly virtual exercise sessions or a health education class. The main goal is to see if they can stand up …

This study tests whether monthly nurse-led coaching sessions over a year can help people with mild cognitive impairment or dementia and their caregivers. Researchers will track symptoms, quality of life, and how well care plans are documented. The goal is to improve supportive ca…

This small study tested whether a non-invasive brain stimulation technique called tDCS can be used safely at home to reduce seizures in people with epilepsy. Four adults with hard-to-control seizures used the device daily for several weeks. Researchers tracked seizure counts, sev…

This Stanford study tests whether a bioactive fabric sleeve worn after pitching can reduce next-day arm soreness in college baseball players. Thirteen pitchers will wear either the bioactive sleeve or a control sleeve overnight after games and rate their soreness. The goal is to …

This study tests a web-based decision aid called 'Roadmap to Parenthood' for young women who have completed cancer treatment and are thinking about having children. The tool provides information and planning support to help them make informed choices. Researchers will measure whe…

This study aimed to see if putting up fake windows that show outdoor scenes could improve the mood of teachers working in classrooms without real windows. It was planned for teachers at one school in New York, but the study was withdrawn before any teachers joined. No results are…

This study tests whether adding a nerve stimulator to standard ultrasound guidance improves the quality of nerve blocks for upper limb surgery. 82 adults having elective arm surgery will be randomly assigned to receive the block with or without the stimulator active. Researchers …

This study tests a mobile app called Stanford SpineKeeper to help people with chronic low back pain. Participants choose a track focused on relaxation or increasing activity, using educational materials from trusted health organizations. The goal is to see if the app can improve …

This study tests whether a computer-based AI tool can teach glaucoma patients how to take a visual field test more accurately. The test checks side vision, which is important for monitoring glaucoma. If the tool works, it could lead to more reliable results, fewer repeat visits, …

This study tests a small vibrating device held near the skin during needle sticks (like IVs or blood draws) to see if it lowers pain and anxiety. About 1,100 children and adults will take part. Researchers will watch and ask about discomfort to see if the buzz helps people feel c…

This study tests a quick, non-invasive brain stimulation method called accelerated intermittent theta-burst stimulation (aiTBS) to see if it can improve mood in people with borderline personality disorder (BPD) who are also experiencing a major depressive episode. About 45 adults…

This study tests whether a single, two-hour pain relief skills session called Empowered Relief can reduce chronic pain after a cesarean delivery. Sixty women who still have moderate to severe pain six weeks after their C-section will attend the session and be followed for 12 week…

This study tests whether a home-based program called Tap Trust can help preschool-aged children and their parents drink more tap water. The program provides water testing kits, filters if needed, reusable bottles, and coaching sessions. Researchers will measure changes in water i…

This study tests whether adding a blood flow restriction (BFR) cuff to low-weight hand exercises can help people with ulnar-sided wrist pain recover faster. 90 adults will be assigned to either standard therapy or therapy plus BFR. The goal is to see if BFR improves grip strength…

This study tests whether a single dose of ketamine, given while patients are sedated, can reduce chronic pain and depression symptoms. Forty adults with both conditions will receive either ketamine or a placebo (saline) during sedation with propofol. Researchers will track pain a…

This pilot study aimed to see if it is possible to use neuropsychological tests to measure thinking, memory, and emotional health in adults who received CAR-T therapy for aggressive lymphoma at least six months earlier. The study was withdrawn before enrolling any participants, s…

This early-stage study at Stanford University compares ketamine to a placebo (saline) during sedation in 15 healthy adults with major depressive disorder. The goal is to see how these drugs affect brain activity and experiences like dreams or thoughts. Researchers will use EEG to…

This study tests whether a simple questionnaire, filled out by children and teens with cancer (and their caregivers) before and after a clinic visit, can help doctors better understand their symptoms. About 85 participants will use the tool during routine visits. The goal is to s…

This study at Stanford University is testing whether wearable devices like smartwatches can help measure fatigue, sleep, and daily activity in people with primary biliary cholangitis (PBC), a chronic liver disease. Researchers will compare data from the wearables with patient que…

This pilot study aimed to test a new breast-dedicated PET camera that can see details as small as 1 millimeter. Researchers planned to inject a radioactive tracer into people with breast cancer and see if the camera could produce clear images. However, the study was withdrawn bef…

This study looks at whether improving sleep through cognitive behavioral therapy (CBT-I) can reduce neuropsychiatric symptoms like anxiety, depression, and agitation in 150 older adults with mild cognitive impairment or early Alzheimer's. Participants are randomly assigned to CBT…

This Stanford study is testing whether non-intrusive sensors placed in the home can automatically track neuropsychiatric symptoms like mood changes and agitation in older adults. Researchers will enroll 25 participants with or at risk of mild cognitive impairment or dementia, alo…

This study looks at how immune cells in different types of body fat (belly fat vs. fat under the skin) are linked to insulin resistance, a condition where the body doesn't use insulin well. Researchers will analyze fat samples from 50 people having weight-loss surgery to see if c…

This early-phase study at Stanford University is testing whether the medication droperidol can change how much patients like the feeling of fentanyl, a common painkiller given during procedures. About 130 adults scheduled for surgery will receive either droperidol or a placebo, a…

This study was designed to see if a new type of airway device can prevent dangerous drops in oxygen levels during anesthesia in patients who are at high risk, such as those with obesity or sleep apnea. Researchers planned to compare the new device with standard ones in adults und…

This study planned to use Apple Watches to track physical activity, diet, and environment in children with complex regional pain syndrome (CRPS) to identify what triggers sudden severe pain. However, the study was withdrawn before enrolling any participants, so no data was collec…

This study looks at how fentanyl changes brain activity using EEG (a brain wave test) in 20 adults having surgery. Researchers want to find a specific brain signal linked to fentanyl and see if it relates to how much people like the drug. No new treatment is tested—only brain pat…

This study aimed to help 4th graders develop healthy bladder habits by providing education, water stations, and changes to classroom bathroom policies. Researchers planned to track bathroom use, symptom scores, and urine volume. However, the study was withdrawn before enrolling a…

This study aimed to see if conversational AI simulations could help anesthesiology trainees improve their communication skills for difficult talks, like telling a patient about a medical error. It planned to include healthcare workers who talk with patients daily. However, the st…

Stanford University is testing whether artificial intelligence can help medical interns learn to use ultrasound more effectively. In this study, 150 internal medicine residents will be randomly assigned to use a handheld ultrasound device with or without AI assistance. Researcher…

This study looks at 600 adults with non-compaction cardiomyopathy, a rare heart muscle condition that can lead to heart failure, stroke, or dangerous heart rhythms. Researchers will use heart scans, genetic tests, and health records to find better ways to predict who is at highes…

This study aimed to see if anesthesiology residents in Hong Kong could use augmented reality (AR) to practice crisis skills with experts in the United States. The focus was on non-technical skills like teamwork and decision-making. However, the study was withdrawn before any part…

This pilot study aimed to see if personalized lifestyle coaching and a simple handout could help emergency medicine residents stay alert and perform better during night shifts. The study planned to compare coached residents to those receiving only a handout, measuring reaction ti…

This study was designed to compare two standard surgical techniques for bicep tenodesis—using one anchor or two mini anchors—to see which keeps the tendon in place better. It planned to track tendon movement with X-rays right after surgery, at 2 weeks, and at 6 months. However, t…

Researchers at Stanford are creating a database to better understand why some older adults experience memory or thinking problems after surgery with anesthesia. They will collect information from 250 patients aged 65 and older, including blood samples, brain wave recordings, and …

This study looks at how eating fermented and fiber-rich foods during pregnancy changes the gut bacteria of mothers and their babies. Researchers will track 135 pregnant women and their infants to see if diet affects the types of bacteria passed from mom to baby. The goal is to le…

This study tests whether an AI-powered speech-to-text tool can accurately capture health information from heart failure patients. Researchers at Stanford will enroll 100 adults with heart failure to see if the tool's summaries match expert reviews. The goal is to improve communic…

This study was designed to learn why some children with type 1 diabetes, especially those with public insurance, do not use helpful diabetes technology like continuous glucose monitors. Researchers planned to interview and survey healthcare providers to understand barriers and fi…

This study tests whether focused ultrasound to the brain can change how the anesthetic propofol works. Ten healthy adults will receive both real and fake ultrasound while under sedation. Researchers will measure brain signals and response times to see if ultrasound alters anesthe…

This study looks at whether giving pharmacists extra education plus monthly feedback on their performance helps them adjust heart failure medications more often than just education alone. About 400 pharmacists across 22 VA sites will take part. The goal is to see if simple change…

This study aimed to find out if removing the nail plate helps people with nailbed injuries heal better. It was planned by Stanford University but was withdrawn before any participants were enrolled. No data or results are available from this trial.

This study aimed to see if a mobile monitoring tool could accurately identify surgical site infections (SSIs) in orthopedic surgery patients, compared to the usual manual review. The study was withdrawn before enrolling any participants, so no results are available. It was design…

This study aimed to see if notifying patients and their primary care doctors about calcium buildup in heart arteries (found on a prior chest CT) would increase the number of people starting cholesterol-lowering statins. It planned to include adults aged 18-84 with moderate to sev…

This study from Stanford University aims to find biological markers that can tell doctors whether a person with chronic musculoskeletal pain is likely to recover or develop long-term disability. Researchers will follow 250 adults aged 18-80, using questionnaires and possibly imag…

This study aimed to see if telling patients and their doctors about calcium buildup in heart arteries (found on lung cancer scans) would lower the chance of death, heart attack, or stroke. It was designed for adults without known heart disease who had a lung scan showing signific…

This study looks at whether brain scans can help predict which veterans with hard-to-treat depression will get better with a treatment called transcranial magnetic stimulation (TMS). Researchers will use MRI scans to measure brain activity before and during TMS therapy. The goal …

This study tests whether a custom AI chatbot can help cataract patients better understand their artificial lens choices before meeting their surgeon. About 70 adults will either get standard counseling or standard counseling plus an AI explanation. The goal is to see if the AI to…

This study looks at whether a parent coaching and family navigation program (Project AFECT) can help families right after a child is diagnosed with autism. About 200 parents of children aged 1 to 5, who are Hispanic/Latino, Black/African-American, or have Medi-Cal insurance, will…

This research study collects blood, tumor tissue, and other body fluids from 1,000 adults with lung cancer, thymus cancer, or mesothelioma. The goal is to analyze these samples to find biological markers that could predict how the disease will progress or which treatments might w…

This study collects blood and tissue samples from people receiving or donating bone marrow transplants for leukemia, lymphoma, or other blood diseases. Researchers will analyze these samples to find genes and proteins linked to cancer development and transplant complications. The…

This study aimed to see if changing how cancer patients think about their illness could improve their quality of life and treatment outcomes. Researchers planned to follow newly diagnosed patients and give some a short mindset training. However, the study was withdrawn before any…

This study aims to identify brain-based subtypes of Obsessive-Compulsive Disorder (OCD) and see how they respond to two different targets of repetitive transcranial magnetic stimulation (rTMS). Researchers will use brain scans to measure connectivity in specific networks before a…

This Stanford study compares high-intensity interval training (HIIT) with moderate-intensity continuous training (MICT) in 135 healthy but sedentary adults. Over 12 weeks, participants will exercise three times a week for about an hour. Researchers will measure changes in fitness…

This study looks at how two parts of the thalamus (ANT and PLV) are connected to other brain areas and how they are involved in seizures and memory. Researchers will record brain activity from 100 epilepsy patients who already have electrodes implanted for medical reasons. The go…

This study tests a new imaging technique called Deuterium Metabolic Imaging (DMI) to see if it can predict how well glioblastoma patients respond to treatment. Ten participants will drink a special glucose tracer before MRI scans. The goal is to improve treatment decisions, but t…

This study aimed to see if a fast-acting form of brain stimulation (called accelerated TMS) could change brain activity linked to suicidal thinking in adults hospitalized for major depression. The researchers planned to measure changes in suicidal thoughts using a standard questi…

This study follows 275 teens aged 11–18 with chronic muscle or joint pain to find biological and behavioral markers that predict recovery versus ongoing pain. Researchers measure pain intensity and how much pain limits daily activities. The goal is to better understand why some t…