New scan could spare men with prostate cancer from unnecessary biopsies

NCT ID NCT05948657

Recruiting now Diagnosis Sponsor: Weill Medical College of Cornell University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a special type of PET/CT scan (PSMA-PET CT) can accurately detect aggressive prostate cancer in men who are on active surveillance (watchful waiting). Researchers will scan 200 men with low- or favorable intermediate-risk prostate cancer at the start, then at 12 and 24 months, and compare the results to biopsies. The goal is to see if the scan can reliably rule out significant cancer, potentially reducing the need for frequent invasive biopsies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: PSMA-PET CT scan
What this could lead to: If successful, this could make active surveillance safer and more accurate, helping men avoid unnecessary biopsies and treatments.
What could go wrong: This is an early-stage diagnostic study, not a treatment trial. The scan may not be accurate enough to replace biopsies, and results may not apply to all prostate cancer patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER

Contacts and locations

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Study contacts

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Locations

UCLA
NOT_YET_RECRUITING

Los Angeles, California, 90005, United States

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UCSF
NOT_YET_RECRUITING

San Francisco, California, 94143, United States

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UH Cleveland Medical Center
RECRUITING

Cleveland, Ohio, 44106, United States

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Weill Cornell Medicine - New York Presbyterian Hospital
RECRUITING

New York, New York, 10065, United States

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