Could your own bone marrow fix jaw pain? new trial tests it
NCT ID NCT07536399
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests whether injecting a concentrate of your own bone marrow (BMAC) into the jaw joint during arthroscopy reduces pain and damage better than a standard steroid shot. Twenty adults with long-lasting TMJ pain will be randomly assigned to one of the two treatments and followed for 6 months with questionnaires and MRIs. The goal is to see if this natural approach can calm inflammation and improve jaw function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Bone marrow aspirate concentrate (BMAC) and corticosteroid
What this could lead to
If BMAC works better than steroids, it could offer a longer-lasting, natural treatment for TMJ pain and joint damage.
What could go wrong
This is a small, early-phase trial with only 20 people. BMAC is experimental for TMJ, and results may not apply to everyone. Risks include pain or infection from the bone marrow harvest.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Weill Cornell Medical College - NewYork-Presbyterian Hospital
New York, New York, 10024, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••