Small study seeks best numbing dose for skin surgery

NCT ID NCT06694714

Recruiting now Knowledge-focused Sponsor: Weill Medical College of Cornell University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing how long two different volumes of a common numbing medicine (lidocaine with epinephrine) keep the skin numb during dermatologic surgery. Researchers will inject either 0.5 ml or 1.0 ml into the side of the nose in 35 adults and check every 15 minutes when feeling returns. The goal is to see if a larger volume provides a meaningfully longer numbing effect.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lidocaine with epinephrine
What this could lead to: If successful, this could help doctors choose the best anesthetic volume for numbing highly vascular skin areas, improving patient comfort during minor surgery.
What could go wrong: This is a small, early-phase study (35 participants) focused on measuring numbness duration, not on treating a disease. Results may not apply to other body sites or anesthetics.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANESTHESIA, LOCAL

Contacts and locations

Locations

Weill Cornell Medicine
RECRUITING

New York, New York, 10021, United States

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