New prostate surgery technique aims to reduce side effects without sacrificing cancer control
NCT ID NCT05155501
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a standard robot-assisted prostate removal surgery to a newer, pelvic fascia-sparing approach that aims to preserve nerves and support structures. Researchers will enroll 600 men with localized prostate cancer to see if the new technique offers similar cancer control while improving urinary function and reducing complications like penile shortening or hernias. Participants will be randomly assigned to one of the two surgical methods and followed for cancer recurrence and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
robot-assisted radical prostatectomy (standard and pelvic fascia-sparing)
What this could lead to
If successful, this could show that a less invasive surgical technique provides similar cancer control with better urinary function and fewer side effects.
What could go wrong
This is a surgical technique comparison, not a new drug or cure. Results may not apply to all prostate cancer patients, and the new approach may not improve outcomes as hoped.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
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Locations
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Beckman Research Institute of City of Hope
RECRUITINGDuarte, California, 91010, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Beth Israel Deaconess Medical Center (BIDMC)
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Contact Email: •••••@•••••
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Georgetown University
RECRUITINGWashington D.C., District of Columbia, 20007, United States
Contact Email: •••••@•••••
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Hackensack Meridian Health
RECRUITINGHackensack, New Jersey, 07601, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21287, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
Contact
Contact Email: •••••@•••••
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NewYork-Presbyterian Queens
RECRUITINGFlushing, New York, 11355, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Weill Cornell Medicine
RECRUITINGNew York, New York, 10065, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••