New prostate surgery technique aims to reduce side effects without sacrificing cancer control

NCT ID NCT05155501

Recruiting now Disease control Sponsor: Weill Medical College of Cornell University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a standard robot-assisted prostate removal surgery to a newer, pelvic fascia-sparing approach that aims to preserve nerves and support structures. Researchers will enroll 600 men with localized prostate cancer to see if the new technique offers similar cancer control while improving urinary function and reducing complications like penile shortening or hernias. Participants will be randomly assigned to one of the two surgical methods and followed for cancer recurrence and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: robot-assisted radical prostatectomy (standard and pelvic fascia-sparing)
What this could lead to: If successful, this could show that a less invasive surgical technique provides similar cancer control with better urinary function and fewer side effects.
What could go wrong: This is a surgical technique comparison, not a new drug or cure. Results may not apply to all prostate cancer patients, and the new approach may not improve outcomes as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER

Contacts and locations

Locations

Beckman Research Institute of City of Hope
RECRUITING

Duarte, California, 91010, United States
Beth Israel Deaconess Medical Center (BIDMC)
RECRUITING

Boston, Massachusetts, 02215, United States
Georgetown University
RECRUITING

Washington D.C., District of Columbia, 20007, United States
Hackensack Meridian Health
RECRUITING

Hackensack, New Jersey, 07601, United States
Johns Hopkins University
RECRUITING

Baltimore, Maryland, 21287, United States
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States
NewYork-Presbyterian Queens
RECRUITING

Flushing, New York, 11355, United States
Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States
Weill Cornell Medicine
RECRUITING

New York, New York, 10065, United States

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