KNEE PAIN CHRONIC
Clinical trials for KNEE PAIN CHRONIC explained in plain language.
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New knee implant aims to repair cartilage and ease pain
Disease control Recruiting nowThis trial tests a new partial knee implant called BioPoly for people with knee cartilage damage and pain. Participants are randomly assigned to receive either the implant or standard surgery (microfracture or debridement). The study measures success by pain and function improvem…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: BioPoly LLC • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Brain training may beat usual care for Post-Surgery knee pain
Symptom relief Recruiting nowThis study tests Pain Reprocessing Therapy (PRT) for adults with ongoing knee pain after knee replacement surgery. PRT uses eight weekly video sessions to help retrain how the brain processes pain. Researchers will compare PRT to usual care in 110 participants to see which better…
Matched conditions: KNEE PAIN CHRONIC
Phase: PHASE2 • Sponsor: Weill Medical College of Cornell University • Aim: Symptom relief
Last updated Aug 07, 2026 00:00 UTC
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Vitamin c trial aims to ease persistent pain after knee surgery
Symptom relief Recruiting nowThis study tests whether taking vitamin C around the time of knee replacement surgery can reduce long-term pain. About 400 adults having knee replacement will be randomly assigned to receive vitamin C or a placebo for 8 weeks. The main goal is to see if a larger study is possible…
Matched conditions: KNEE PAIN CHRONIC
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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Shockwaves could ease stubborn knee pain without surgery
Symptom relief Recruiting nowThis study tests if focused shockwave therapy can safely reduce knee pain and improve function in people with osteoarthritis who have bone marrow lesions. Fifteen adults with persistent knee pain will receive four weekly shockwave sessions or standard care (pain relievers and res…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Kessler Foundation • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Light therapy shines as potential Drug-Free knee pain relief
Symptom relief Recruiting nowThis study tests whether a special light (810 nm) can reduce knee pain and swelling in people with chronic knee pain and synovitis. About 80 adults aged 40-80 will receive either real light therapy or a sham treatment twice a week for five weeks. Researchers will measure pain, ul…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: The Hong Kong Polytechnic University • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Brain scans may reveal who will be satisfied after knee surgery
Knowledge-focused Recruiting nowThis study looks at whether brain scans can predict if someone will be satisfied after knee replacement surgery. Up to 1 in 5 patients still have pain or trouble moving after surgery, and doctors can't currently predict who. Researchers will scan the brains of 50 adults before an…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Ottawa Hospital Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC