New knee implant aims to repair cartilage and ease pain

NCT ID NCT06915363

Recruiting now Disease control Sponsor: BioPoly LLC Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This trial tests a new partial knee implant called BioPoly for people with knee cartilage damage and pain. Participants are randomly assigned to receive either the implant or standard surgery (microfracture or debridement). The study measures success by pain and function improvement and whether additional knee surgery is needed within two years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: BioPoly partial resurfacing knee implant
What this could lead to: If successful, this implant could offer a more effective, longer-lasting option for repairing knee cartilage damage, potentially delaying or avoiding total knee replacement.
What could go wrong: This is a pivotal trial, but the implant is still investigational. It may not outperform standard surgery, and risks include implant failure, infection, or need for additional surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CARTILAGE DAMAGE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

articular cartilage disorder osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARTILAGE DAMAGE CARTILAGE DEFECTS OF THE KNEE CARTILAGE LESION CARTILAGE OR OSTEOCHONDRAL DEFECTS IN THE KNEE KNEE OSTEOARTHRITIS KNEE PAIN CHRONIC

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Dupont Hospital
RECRUITING

Fort Wayne, Indiana, 46845, United States

Contact
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
OrthoIndy
RECRUITING

Indianapolis, Indiana, 46278, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Washington University Orthopedics
RECRUITING

Chesterfield, Missouri, 63017-5701, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.