Can a Screen-Based tai chi class soothe aching knees?
NCT ID NCT06384898
First seen Sep 04, 2026 · Last updated Sep 04, 2026
Summary
This trial tests whether remote tai chi, taught through web-based sessions twice a week for 12 weeks, can reduce knee pain in adults aged 50 and older with knee osteoarthritis. Researchers compare adding remote tai chi to routine care against routine care alone, measuring pain, pain interference, and quality of life at 3 months, and tracking healthcare use and painkiller intake over a year. The goal is to see if a mind-body exercise program delivered at home can be a practical, non-drug option for managing osteoarthritis pain.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Remote Tai Chi, a mind-body exercise program delivered via web-based sessions twice a week for 12 weeks
- What this could lead to
- If it works, remote tai chi could offer a convenient, drug-free way to reduce knee pain and improve quality of life for many older adults with knee osteoarthritis.
- What could go wrong
- This is a pragmatic trial, not a lab-controlled study, so results may vary in real-world settings. Tai chi may not ease pain for everyone, and participants must stick with the 12-week program to see benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 480 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2025
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 100 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 50 years or older * Treating clinician diagnosis of knee osteoarthritis * Have a score of 40 (visual analog version) or greater on at least 1 of the 5 questions in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain subscale (range of 0 to 100, with higher scores indicating greater pain) at baseline. * Able to provide informed consent * If randomized to the Routine Care group, willing to abstain from Tai Chi programs until completion of the study * If randomized to the Tai Chi group, willing to comply with the Tai Chi program (twice-a-week remote sessions for 12 weeks) * Has access to a home computer or device that will allow telehealth (bidirectional audio and video) delivery of the intervention * Is an active patient at one of the 4 participating healthcare system Exclusion Criteria: * Currently practicing Tai Chi * Serious medical conditions (e.g., dementia, significant neurological deficits or neurodegenerative disorder, active cancer treatment, psychosis, sensory deficits) limiting the participant's ability to participate in the Tai Chi safely, as determined by the principal investigators * Unable to walk without a cane or other assistive device * Any previous or scheduled knee replacement * Reports severe depression defined by a Beck Depression Inventory (BDI-II) score of 29 or more. * Reports suicidal ideations defined by a score on BDI-II item of 2 or 3 ('I would like to kill myself' or 'I would kill myself if I had the chance'). * Not English speaking * Enrollment in any other clinical trial within the last 30 days
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Tufts Medical Center
RECRUITINGBoston, Massachusetts, 02111, United States
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