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Can a daily drink soothe aching knees?

NCT ID NCT07800676

Symptom relief Sponsor: Taipei Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time

Summary

Researchers are testing whether a daily drink containing hyaluronic acid can ease knee pain and improve joint function in adults aged 45 to 80 with mild knee osteoarthritis. Participants will drink either the active beverage or a placebo each day and report their pain levels using standard scales. The trial aims to see if this simple supplement offers a practical way to manage chronic knee discomfort.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A+HA premium oral hyaluronic acid drink
What this could lead to
If it works, this drink could offer a simple daily option for easing knee pain and improving joint function in people with mild osteoarthritis.
What could go wrong
This is a small early-stage trial with only 60 participants, so results may not apply to everyone. The drink may not outperform a placebo, and any benefit could be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Aged 45 to 80 years. 2. Knee osteoarthritis classified as Ahlbäck stage I or II, or Kellgren-Lawrence grade \<3. 3. A Visual Analogue Scale (VAS) pain score ≤3. 4. A Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain subscale score \>2 or a total WOMAC score \>12. Exclusion Criteria: 1. Pregnant or breastfeeding women. 2. Individuals with a history of knee joint trauma or surgery. 3. A body mass index (BMI) ≥ 40 kg/m². 4. Individuals with a psychiatric disorder. 5. Individuals with severe cardiovascular disease, severe cerebrovascular disease, severe rheumatic disease, crystal deposition arthropathy, or cancer. 6. Individuals who use a wheelchair and have a Manual Muscle Testing (MMT) grade ≤3 in the lower extremities, or who require a wheelchair due to physical discomfort. 7. Use of anti-inflammatory analgesics, corticosteroids, or other medications that may affect the study outcomes within one week before the trial. 8. Receipt of intra-articular corticosteroid injections, hyaluronic acid injections, platelet-rich plasma (PRP) therapy, or nerve block treatment within one month before the trial. 9. Use of medications or consumption of foods that, in the judgment of a physician or dietitian, may affect the outcome measures. 10. Any other condition considered by the physician to make the individual unsuitable for participation in the trial.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee pain chronic

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Taipei Medical University

    Taipei, Taiwan

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