KNEE PAIN CHRONIC
Clinical trials for KNEE PAIN CHRONIC explained in plain language.
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Knee replacement showdown: cementless vs cemented – which is better?
Disease control OngoingThis study compares two types of total knee replacements: one that uses bone cement to hold the implant in place and one that does not. The goal is to see which approach provides better pain relief, function, and implant survival over time. About 300 adults with knee arthritis or…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Zimmer Biomet • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New knee implant put to the test in 269 patients
Disease control OngoingThis study looks at how well a partial knee replacement device called MOTO Medial® works for people with knee arthritis. About 269 adults with arthritis in the inner part of the knee will get the implant and be followed for several years. Researchers will measure pain, movement, …
Matched conditions: KNEE PAIN CHRONIC
Sponsor: Medacta USA • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New knee implant study tracks Long-Term success
Disease control OngoingThis study follows 737 people who received the Persona knee implant to see how well it works over time. Participants had severe knee pain from conditions like arthritis or injury. The goal is to measure implant survival and improve knee function.
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Zimmer Biomet • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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New knee implant tested for safety and better movement
Disease control OngoingThis study is testing a new knee implant called Persona Ti-Nidium in 240 adults who need a total knee replacement due to arthritis or other knee problems. The goal is to see if the implant is safe and helps people move better and feel less pain. Participants will have surgery and…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Zimmer Biomet • Aim: Disease control
Last updated May 11, 2026 20:47 UTC
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New nerve zap device could ease arthritic knee pain without surgery
Symptom relief OngoingThis study tests whether a device that stimulates nerves near the spine (dorsal root ganglion) can reduce chronic knee pain caused by osteoarthritis. About 30 adults with long-term knee pain who have not had surgery or are not good candidates for it will receive the implant. The …
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Kenneth B Chapman • Aim: Symptom relief
Last updated May 17, 2026 02:40 UTC
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New tool helps knee patients get clear on their goals
Symptom relief OngoingThis study tests a simple goal-setting tool for people with knee pain or injury who are seeing an orthopedic surgeon. The tool helps patients identify specific, measurable, and time-bound goals for their treatment. The goal is to improve shared decision-making and make sure patie…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated May 17, 2026 02:26 UTC
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Knee replacement patients may get lasting pain relief from nerve surgery
Symptom relief OngoingThis study tests whether cutting a small nerve in the knee during a total knee replacement can lessen chronic pain after surgery. About 178 adults having their first knee replacement took part. The goal is to see if this extra step improves pain relief compared to the standard pr…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated May 13, 2026 16:00 UTC
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Desperate knee pain patient gets experimental stem cell treatment
Symptom relief NO_LONGER_AVAILABLEThis study tested a stem cell treatment in one person with long-term knee pain from osteoarthritis who had no other options left. The patient received stem cells from their own fat, given through a vein and directly into both knees. The goal was to see if it is safe and if it can…
Matched conditions: KNEE PAIN CHRONIC
Sponsor: Hope Biosciences Research Foundation • Aim: Symptom relief
Last updated May 11, 2026 20:47 UTC