KNEE PAIN CHRONIC
Clinical trials for KNEE PAIN CHRONIC explained in plain language.
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Custom-Fit knee implants put to the test in Decade-Long study
Disease control OngoingThis study is following 240 people for 10 years after they receive a specific brand of personalized knee replacement. Researchers want to see how safe the implant is and how well it relieves pain and improves movement for people with severe knee arthritis. The study tracks patien…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Tracking a decade of data on new knee implants
Disease control OngoingThis study is following people who received a specific type of knee replacement, called the Persona implant, to see how well it works and how long it lasts over ten years. It includes adults with severe knee pain from conditions like arthritis who need a total knee replacement. R…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Knee replacement showdown: cemented vs cementless implants
Disease control OngoingThis study compares two types of knee replacement implants—one that uses bone cement and one that doesn't—to see which provides better long-term results. Researchers will follow 300 patients with severe knee arthritis for up to 5 years after surgery, measuring pain levels, knee f…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Mar 19, 2026 14:55 UTC
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New knee implant aims to ease arthritis pain
Disease control OngoingThis study is testing how well a specific partial knee replacement implant works for people with arthritis on the inner side of their knee. It follows 269 patients for up to 5 years after surgery to measure changes in pain, knee function, and daily activities. Researchers will al…
Matched conditions: KNEE PAIN CHRONIC
Sponsor: Medacta USA • Aim: Disease control
Last updated Mar 16, 2026 15:26 UTC
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Last hope: one Man's own cells injected to fight debilitating knee pain
Symptom relief NO_LONGER_AVAILABLEThis was a special access program for one individual with severe, untreatable pain in both knees from arthritis. The goal was to see if using the patient's own stem cells, given through an IV and injections directly into the knees, was safe and could reduce pain. The patient rece…
Matched conditions: KNEE PAIN CHRONIC
Sponsor: Hope Biosciences Research Foundation • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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Spinal implant offers new hope for untreatable knee pain
Symptom relief OngoingThis study is testing if a small implanted device that gently stimulates spinal nerves can reduce chronic pain from knee arthritis. It will involve 30 adults with long-term knee pain who haven't gotten enough relief from other treatments like physical therapy or injections. Parti…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Kenneth B Chapman • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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New nerve technique could ease pain after knee surgery
Symptom relief OngoingThis study is testing if a small change during knee replacement surgery can help reduce pain afterwards. Researchers are comparing two ways of handling a specific nerve in the knee. One method is the standard approach; the other involves tucking the nerve end into soft tissue to …
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC