Knee replacement showdown: cementless vs cemented – which works best?

NCT ID NCT05630053

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 26 times

Summary

This study compares two types of total knee replacement implants: one that uses bone cement to hold it in place and one that doesn't. The goal is to see which one provides better pain relief, function, and long-term survival. About 300 adults with knee arthritis or other knee conditions will be followed for up to 5 years after surgery.

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Contacts and locations

Locations

  • Anderson Orthopaedic Research Institute

    Alexandria, Virginia, 22306, United States

  • Centura Health

    Westminster, Colorado, 80023, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21224, United States

  • Lehigh Valley Hospital - Dickson City

    Dickson City, Pennsylvania, 18519, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Oregon Health & Science University

    Portland, Oregon, 972329, United States

  • Rothman Institute

    Bryn Mawr, Pennsylvania, 19010, United States

Conditions

Explore the condition pages connected to this study.