Could a common diabetes drug help prostate cancer patients?

NCT ID NCT05515978

Recruiting now Disease control Sponsor: University of Colorado, Denver Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether metformin, a drug used for diabetes, can help prostate cancer patients who have high blood sugar or are overweight. About 100 men will either take metformin plus get lifestyle advice, or just get lifestyle advice. The main goal is to see if it's possible to run this kind of study, not yet to prove the drug works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Metformin (a diabetes drug)
What this could lead to: If successful, this could show that metformin helps manage weight and blood sugar in prostate cancer patients, potentially improving their overall health.
What could go wrong: This is a very early feasibility study with only 100 participants. It is not designed to prove metformin affects prostate cancer itself, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

neoplasm prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER

Contacts and locations

Locations

Colorado Research Center
RECRUITING

Aurora, Colorado, 80045, United States
UCHealth-Metro Denver
RECRUITING

Denver, Colorado, 80217-3364, United States
UCHealth-Northern Colorado
RECRUITING

Fort Collins, Colorado, 80521, United States
UCHealth-Southern Colorado
RECRUITING

Colorado Springs, Colorado, 80863, United States

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