New CAR t therapy targets hidden leukemia cells in early remission

NCT ID NCT05535855

First seen Nov 15, 2025 · Last updated May 13, 2026 · Updated 26 times

Summary

This early-phase trial tests whether a new type of CAR T cell therapy (UCD19) is safe and can work in adults with B-cell acute lymphoblastic leukemia (B-ALL) who are in first remission but still have tiny amounts of cancer cells (minimal residual disease). About 29 participants will receive the treatment after chemotherapy. The study will monitor side effects and check if the therapy can clear remaining cancer cells and prevent relapse.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • University of Colorado Hospital

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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