Could ozempic protect hearts in type 1 diabetes? new trial aims to find out

NCT ID NCT05819138

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial is testing whether semaglutide, a drug already used for type 2 diabetes and weight loss, can improve heart and kidney function in adults with type 1 diabetes. The study will measure artery stiffness, insulin sensitivity, and kidney blood flow in 60 participants over time. Semaglutide is not FDA-approved for this use, so the results will help determine if it could become a new treatment option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

semaglutide (Ozempic)

What this could lead to

If it works, this could point toward a new way to protect heart and kidney health in people with type 1 diabetes.

What could go wrong

This is a small, early-phase trial in type 1 diabetes, and semaglutide is not yet approved for this use. It may not show the same benefits seen in type 2 diabetes, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

type 1 diabetes mellitus type 1 diabetes mellitus 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Colorado Anschutz Medical Campus

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Washington Medicine Diabetes Institute (UWMDI)

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact