Weekly chemo could be easier on elderly sarcoma patients

NCT ID NCT07125183

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving the chemotherapy drug doxorubicin weekly at a lower dose is effective and easier to tolerate for people aged 65 to 100 with advanced leiomyosarcoma, a type of soft tissue cancer. The standard dose often causes harsh side effects, especially in older or frailer patients. Researchers will track how long the cancer stays under control and how patients feel during treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

doxorubicin (a chemotherapy drug)

What this could lead to

If successful, this could offer a better-tolerated chemotherapy option for elderly patients with advanced leiomyosarcoma, potentially improving quality of life while controlling tumor growth.

What could go wrong

This is a small early-phase trial with only 20 participants, so results may not apply broadly. The lower dose may also be less effective at stopping cancer progression.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

leiomyosarcoma sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Of Colorado Hospital

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••