Unlocking the mystery of persistent pain after breast surgery

NCT ID NCT03408717

First seen Aug 07, 2026 ยท Last updated Aug 07, 2026

Summary

This study is looking at why some people develop persistent pain after breast cancer surgery while others do not. Researchers will follow 220 adults undergoing breast cancer surgery, using questionnaires and a pain sensitivity test to identify risk factors. The goal is to find reliable predictors of long-term pain, which could help doctors personalize pain management and improve recovery.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Questionnaires and mechanical temporal summation assessment
What this could lead to
If successful, this could lead to better ways to identify patients at high risk for persistent pain after breast surgery, enabling earlier interventions and improved pain management.
What could go wrong
This is an observational study, so it cannot prove cause and effect. The findings may not apply to all patients or settings, and the risk factors identified may not be reliable enough for clinical use.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • KK Women's and Children's Hospital

    Singapore, 229899, Singapore

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