Can switching meds or using E-Cigs help smokers quit for good?
NCT ID NCT06118502
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether changing treatment can help smokers who relapse early after trying to quit. 544 participants who want to quit smoking will receive free nicotine patches, lozenges, varenicline, or e-cigarettes for 12 weeks. All visits are remote, and the study lasts 6 months with 8 surveys.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nicotine replacement therapy (patches/lozenges), varenicline, or e-cigarettes
What this could lead to
If successful, this could provide a personalized strategy to help smokers who struggle to quit with standard medications.
What could go wrong
This is an early-stage behavioral study without a control group, so results may not prove which approach works best. E-cigarettes carry their own health risks.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
Contact Email: •••••@•••••