Could a cancer drug tame lupus in kids?

NCT ID NCT06789107

Recruiting now Disease control Sponsor: Mao Jianhua Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early trial tests if blinatumomab, a drug used for certain blood cancers, can help children with severe lupus that hasn't improved with other treatments. Six children will receive two short courses of the drug and be monitored for a year. The main goals are to check safety and see if lupus symptoms get better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: blinatumomab
What this could lead to: If it works, this could point toward a new treatment option for children with lupus that doesn't respond to standard therapies.
What could go wrong: This is a very early phase 1 trial with only 6 participants, so results may not apply to everyone. The drug may cause side effects or fail to control the disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLINATUMOMAB CHILDREN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

Contacts and locations

Locations

Children's Hospital, Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310051, China
Children's Hospital, Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, China

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