Can a lighter sedative dose keep patients calm after nasal surgery?
NCT ID NCT07740655
First seen Jul 31, 2026 · Last updated Jul 31, 2026
Summary
This trial tests whether a low dose of the sedative remimazolam can prevent emergence agitation—confusion and restlessness during recovery from anesthesia—after nasal surgery. The standard dose can cause excessive sleepiness and brain wave suppression, so researchers want to see if a lower dose works just as well with fewer side effects. Adults aged 18-79 undergoing nasal surgery under sevoflurane anesthesia will receive either a low or standard dose of remimazolam at the end of surgery, and their recovery will be closely monitored.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- remimazolam
- What this could lead to
- If low-dose remimazolam works as well as the standard dose, it could offer a safer way to prevent post-surgery agitation, reducing excessive sedation and brain activity suppression.
- What could go wrong
- This is a small, single-center trial, and the lower dose might not be as effective. There's also a risk of allergic reactions or other side effects from the drug.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Jeju National University Hospital
Jeju City, Jeju-do, South Korea
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