A dab of gel on the breathing tube might spare surgery patients a sore throat — a trial puts it to the test.

NCT ID NCT07040631

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial tests whether applying a hyaluronic acid gel (Endotra Gel) to the breathing tube before general anesthesia can reduce sore throat, hoarseness, and coughing after breast cancer surgery. About 132 adults undergoing breast cancer surgery will be randomly assigned to receive the gel or standard care. Researchers will track symptoms right after surgery and the next day to see if the gel improves comfort and recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a hyaluronic acid-based gel (Endotra Gel) applied to the endotracheal tube cuff before intubation
What this could lead to
If it works, this simple gel application could become a routine way to prevent throat discomfort after surgery under general anesthesia.
What could go wrong
This is a small, early-stage trial. The gel may not reduce symptoms more than standard care, and individual results may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Pusan national university yangsan hospital

    Yangsan, Gyeongsangnam-do, 50612, South Korea

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Other studies related to the condition(s) this trial covers.