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Could a tiny Pre-Dose of muscle relaxant make anesthesia safer and faster?

NCT ID NCT07716891

Knowledge-focused Sponsor: General Hospital of Ningxia Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study tests whether giving a small dose of the muscle relaxant rocuronium before the main dose can help it work faster during general anesthesia. About 108 adults having elective surgery will be randomly assigned to receive either the pre-injection method or the standard single-dose method. Researchers will measure how quickly the drug takes full effect and how it affects heart rate and blood pressure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
rocuronium bromide
What this could lead to
If it works, this approach could make anesthesia induction faster and safer for patients undergoing surgery.
What could go wrong
This is a small, early-stage study focused on timing and vital signs, not on major health outcomes. The results may not apply to all patients or surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 108 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged from 18 to 65 years old * American Society of Anesthesiologists (ASA) physical status classification Ⅰ, Ⅱ or Ⅲ * Elective surgery requiring general anesthesia with tracheal intubation * Able to understand the study and voluntarily sign written informed consent * Male or female, no gender restriction Exclusion Criteria: * Severe hepatic dysfunction (ALT/AST \> 3 times the upper limit of normal) or renal dysfunction (creatinine \> 2 times the upper limit of normal) * Central nervous system diseases or severe neuromuscular disorders * Severe arrhythmia or cardiac dysfunction (NYHA class Ⅲ-Ⅳ, or ejection fraction EF \< 30%) * Known hypersensitivity or allergy to rocuronium, midazolam, propofol or other study-related drugs * Refusal to participate in this clinical trial * Pregnant or breastfeeding women * History of predicted difficult airway requiring awake tracheal intubation * Contraindications to rapid sequence induction

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Elective surgery General anesthesia

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • General Hospital of Ningxia Medical University

    RECRUITING

    Yinchuan, China

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