Can a rough sound reveal how deep anesthesia goes?
NCT ID NCT05283018
First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time
Summary
This trial investigates whether the brain's response to rough sounds can be used to monitor the depth of general anesthesia. Researchers will play monotonous and rough sounds to adults undergoing surgery and record brain activity via EEG, along with blood flow in the brain. The goal is to see if a specific brain wave, called P3a, changes predictably as anesthesia deepens and lightens, potentially offering a more accurate monitoring method than current devices.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Auditory stimulation with rough sounds and EEG monitoring
- What this could lead to
- If successful, this could lead to a more accurate way to monitor brain state during anesthesia, potentially reducing complications like postoperative cognitive dysfunction.
- What could go wrong
- This is an early-stage exploratory study with a small number of participants. The P3a response may not reliably reflect anesthesia depth, and individual variability could limit its usefulness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Expected to start
-
Dec 2023
An estimate. Start dates often move.
- Expected to finish
-
Dec 2024
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients eligible for an outpatient or scheduled surgery procedure under general anesthesia
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Major patients (≥ 18 years old) * Eligible for an outpatient or scheduled surgery procedure under general anesthesia * Patient who expressed his non-opposition to participation in this research Exclusion Criteria: * Patient under the age of 18 * Pre-existing auditory sensorineural impairment * Severe pre-existing cognitive impairment (preoperative mini-mental state examination MMSE \< 24) * Patient opposed to participation in the protocol * Pregnant woman * Patient under judicial protection measure * Patient without affiliation to a social security scheme * Patient benefiting from the State medical assistance (AME) programme
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for General anesthesia are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
AP-HP, Lariboisière Hospital, Department of Anesthesiology and Intensive Care
Paris, 75010, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a targeted nerve block cut opioid use in High-Risk C-Sections?
- Can a new sedative make anesthesia safer for seniors?
- Can a lighter sedative dose keep patients calm after nasal surgery?
- A dab of gel on the breathing tube might spare surgery patients a sore throat — a trial puts it to the test.
- Could a tiny Pre-Dose of muscle relaxant make anesthesia safer and faster?
- Which intubation tool works best? trial puts three devices Head-to-Head