Can a targeted nerve block cut opioid use in High-Risk C-Sections?

NCT ID NCT07748741

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial tests whether an ultrasound-guided erector spinae plane block can reduce pain and the need for opioids during and after cesarean sections in women with placenta accreta, a condition where the placenta grows too deeply into the uterine wall. Participants will receive the nerve block or standard care under general anesthesia, and researchers will measure total opioid use and pain scores over 24 hours. The goal is to see if this nerve block can improve pain control while reducing opioid exposure for both mother and baby.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ultrasound-guided erector spinae plane block (a nerve block procedure)
What this could lead to
If effective, this nerve block could reduce the need for opioids during and after C-sections for placenta accreta, potentially lowering risks for both mother and baby.
What could go wrong
This is a small, early-stage trial, and the nerve block may not provide adequate pain relief in all cases. There are also risks of complications from the procedure itself, such as bleeding or nerve damage.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Kasr Al Aini Hospitals

    Cairo, Egypt

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Other studies related to the condition(s) this trial covers.