Shingles breakthrough? calcitonin shots aim to stop chronic pain before it starts
NCT ID NCT07655804
First seen Jun 25, 2026 · Last updated Jun 25, 2026
Summary
This phase 3 trial tests whether adding daily calcitonin injections to standard shingles treatment can prevent postherpetic neuralgia, a painful nerve condition that can last for months or years. Researchers will enroll 168 adults aged 50 and older who have had a shingles rash for less than a week and are experiencing moderate to severe pain. Participants will receive either calcitonin or a placebo (saline) injection for three weeks, and their pain levels will be checked three months later.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Tanta University Hospitals
Tanta, Gharbia Governorate, 31527, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
calcitonin (salmon calcitonin injection)
What this could lead to
If it works, this could offer a new way to prevent the chronic nerve pain that often follows shingles.
What could go wrong
This is a single-center trial with 168 participants, so results may not apply broadly. Calcitonin can cause allergic reactions, and the benefit over standard care is unproven.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.