Shingles nerve block shows promise in preventing chronic pain

NCT ID NCT07349680

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether an ultrasound-guided nerve block, using a steroid and local anesthetic, could better control pain from shingles and prevent postherpetic neuralgia (long-term nerve pain). 100 adults with acute shingles and moderate to severe pain were randomly assigned to receive either standard medication alone or standard medication plus the nerve block. The main goal was to see how many patients still had significant pain 90 days after the rash started.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bupivacaine and methylprednisolone

What this could lead to

If successful, this nerve block could become a standard add-on treatment to reduce severe shingles pain and lower the chance of developing long-term nerve pain.

What could go wrong

This is a single, completed study with 100 participants. The results may not apply to everyone, and nerve blocks carry risks like infection or bleeding.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

herpes zoster Neuralgia, Postherpetic postherpetic neuralgia prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Marwa Mahmoud Rady

    Asyut, 1987, Egypt