Could a milk thistle extract help Parkinson's patients?
NCT ID NCT07001150
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This Phase 2 trial is testing whether silymarin, an antioxidant from milk thistle, can protect brain cells and improve symptoms in people with Parkinson's disease. Researchers will give 50 adults either silymarin or a placebo alongside their usual Parkinson's medications. The goal is to see if silymarin can slow the disease's progression and ease movement problems.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- silymarin (milk thistle extract)
- What this could lead to
- If it works, this could point toward a new way to slow Parkinson's progression and improve symptom control when added to standard treatment.
- What could go wrong
- This is a small, early Phase 2 trial, so results may not apply to everyone. Silymarin is generally safe, but it may not provide meaningful benefit for Parkinson's symptoms or nerve protection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PARKINSON DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Tanta Hospital for Mental Health
RECRUITINGTanta, Tanta, Qism 2, 31511, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Blood-flow cuffs may mimic exercise to ease Parkinson's symptoms
- Shake or sync: two therapies put to the test for Parkinson's mobility
- Wearable sensors aim to catch neurodegenerative decline in real time
- Can deep brain stimulation rewire faulty movement circuits? a surgery-time study aims to find out.
- The eyes as a window to the brain: can a simple scan monitor MS, Alzheimer's, and Parkinson's?
- Could a simple bowel rinse ease Parkinson's constipation and movement problems?