PRE-ECLAMPSIA

This early-phase study tests whether infusing a woman's own specially prepared natural killer cells into her uterus can improve fertility and pregnancy success. It includes women with recurrent miscarriage, unexplained infertility, or repeated IVF failure linked to abnormal uteri…

This study tests whether the drug dapagliflozin, usually used for diabetes, can reduce the risk of heart problems in women who had high blood pressure during pregnancy. About 200 participants will take either the drug or a placebo daily for six months after giving birth. The goal…

This study tests whether taking low-dose aspirin for 6 months after childbirth can help women who had preeclampsia recover their blood vessel health and lower their blood pressure. About 60 new mothers will receive either aspirin or a placebo. The goal is to see if this simple tr…

This study tests whether adding a specially trained doula to standard care helps women who had high blood pressure during pregnancy get their blood pressure under control after giving birth. About 454 women will be randomly assigned to either usual blood pressure monitoring at ho…

This study tests whether taking 150 mg of aspirin daily, starting before the 20th week of pregnancy, can prevent serious complications like preeclampsia, poor fetal growth, placental abruption, preterm birth, and death in pregnant women with chronic high blood pressure. About 500…

This study tests if starting a higher dose of aspirin early in pregnancy (before 7 weeks) can lower the risk of preeclampsia and pregnancy loss in women with risk factors. About 1,150 pregnant women will take either 162 mg of aspirin daily or a placebo, then switch to a lower dos…

This study tests whether taking vitamin D supplements can prevent preeclampsia from returning in pregnant women who had it before. About 146 women will be randomly assigned to take either vitamin D or a placebo pill until 36 weeks of pregnancy. Researchers will track blood pressu…

This study tests whether taking a daily low-dose aspirin (150 mg) starting early in pregnancy can prevent preeclampsia—a serious condition involving high blood pressure—in first-time mothers who became pregnant through assisted reproductive technology (ART) like IVF. About 1,164 …

This study looks at whether virtual reality (VR) relaxation exercises can help pregnant women with preeclampsia feel less stressed and improve their health and their baby's health. About 96 hospitalized women will be randomly assigned to VR relaxation, in-person relaxation, or st…

This study looks at pregnant women with high blood pressure (pre-eclampsia) to see if a nutrient called 5-MTHF can improve blood vessel function. Researchers will measure levels of a key molecule (BH4) in the blood, placenta, and umbilical cord, and use ultrasound to check heart …

This study looks at how tiny particles released by the placenta, called extracellular vesicles, affect pregnancy complications like pre-eclampsia and gestational diabetes. Researchers will collect samples from 360 pregnant and non-pregnant women to understand these particles' rol…

This study looks at how cells in the placenta die or recycle themselves in pregnant women with conditions like preeclampsia or poor fetal growth. Researchers will compare these cell processes in 50 women to better understand why these complications happen. The goal is to find new…

This study looks at whether early-onset preeclampsia (a serious pregnancy condition) affects the size of certain brain areas in the unborn baby. Researchers will use ultrasound to measure the hippocampus and fornix in 84 pregnant women with and without the condition. The goal is …

This study is exploring whether tiny particles in urine can help predict which pregnant women with high blood pressure will develop pre-eclampsia, a more serious condition. Researchers will measure these particles and other blood markers in 110 pregnant women between 20 and 34 we…

This study follows 462 women who became pregnant through egg donation or standard IVF to learn why pre-eclampsia is more common after egg donation. Researchers will track blood pressure, blood tests, and ultrasounds throughout pregnancy. The goal is to find better ways to predict…

This study looks at why blood vessels behave differently in preeclampsia, a serious pregnancy condition. Researchers will collect tissue from 166 women during C-sections to study a protein called AT2R. The goal is to understand how this protein affects blood vessel function, whic…