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Vitamin d deficiency may undermine dental implants — trial tests if supplements can fix it

NCT ID NCT07684404

Disease control Sponsor: Future University in Egypt Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study tests whether taking vitamin D supplements helps dental implants fuse better with the jawbone in people who are deficient in vitamin D. Ten adults aged 20–60 with low vitamin D levels and a missing tooth in the back of the jaw will receive either vitamin D or no supplement before implant placement. Researchers will measure implant stability right after surgery and check bone loss six months later to see if vitamin D improves healing.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Vitamin D
What this could lead to
If vitamin D improves implant stability and reduces bone loss, it could become a standard pre-treatment for deficient patients, boosting implant success rates.
What could go wrong
This is a very small early trial (10 people) with short follow-up (6 months). Results may not apply to everyone, and vitamin D may not significantly affect implant outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 10 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 20-60 with diagnosed vitamin D deficiency (\<20 ng/mL). * Edentulous area in the posterior mandible or maxilla. * No history of previous dental implant failure, metabolic bone diseases, or conditions affecting bone healing. * Both genders are included Exclusion Criteria: * Severe systemic diseases that could interfere with healing. * Patients already on vitamin D or calcium supplements. * Smokers or patients with poor oral hygiene practices. * Pregnant females

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Conditions

The condition(s) this trial relates to.

vitamin D deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental implant Dental implant failed Vitamin D deficiency

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Future University in Egypt (FUE)

    RECRUITING

    Cairo, New Cairo, 11511, Egypt

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