Could vitamin d play a role in sleep apnea severity?
NCT ID NCT07788391
First seen Aug 26, 2026 · Last updated Aug 27, 2026 · Updated 1 time
Summary
This study looks at whether vitamin D levels differ among adults with and without obstructive sleep apnea (OSA). Researchers will compare blood vitamin D measurements in four groups: healthy controls, simple snorers, OSA patients without other health conditions, and OSA patients with other conditions. Using existing medical records, they will also examine if vitamin D status relates to the severity of sleep apnea. The goal is to better understand any connection between vitamin D and this common sleep disorder.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If a link is found, it could point toward vitamin D as a factor in sleep apnea severity, possibly guiding future prevention or treatment strategies.
- What could go wrong
- This is an observational study using existing records, so it cannot prove cause and effect. Results may be influenced by other health factors and may not apply to everyone.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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269 people
The number who actually took part.
- Started
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Jan 2024
- Finished
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Apr 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consisted of adults evaluated at Hisar Intercontinental Hospital between 2024 and 2026. Participants included a healthy control group and adults who underwent overnight polysomnography because of symptoms suggestive of sleep-disordered breathing. PSG-evaluated participants were classified as simple snoring/non-OSA (AHI \<5 events/hour), OSA without comorbidities, or OSA with comorbidities. The final study population included 269 participants: 81 healthy controls, 49 non-OSA participants, 50 patients with non-comorbid OSA, and 89 patients with comorbid OSA.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Adults aged 18 years or older. Participants with available serum 25-hydroxyvitamin D \[25(OH)D\] measurements. For PSG-evaluated groups, availability of overnight polysomnography data allowing classification according to the apnea-hypopnea index (AHI). Participants meeting the predefined criteria for one of the study groups: healthy control, simple snoring/non-OSA, OSA without comorbidities, or OSA with comorbidities. Exclusion Criteria: Missing or insufficient data required for study-group classification. Missing serum 25(OH)D measurements. Incomplete polysomnographic data preventing determination of OSA status or severity in PSG-evaluated participants.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hisar Intercontinental Hospital
Istanbul, Istanbul, 34768, Turkey (Türkiye)
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