Can a medical food fight malnutrition in IBD?

NCT ID NCT07433946

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a special medical food called LH VIOLA, taken as a partial replacement for regular meals, can help people with Crohn's disease or ulcerative colitis who are at risk of malnutrition maintain or regain weight and muscle strength. About 146 participants will either receive nutritional counseling alone or counseling plus the supplement for 16 weeks. The main goal is to see if more people in the supplement group can keep or gain weight.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

LH VIOLA (a specialized medical food supplement)

What this could lead to

If it works, this could provide a simple nutritional supplement to help IBD patients avoid dangerous weight loss and muscle wasting.

What could go wrong

This is a small, early-stage nutritional study, not a drug trial. The supplement may not significantly improve weight or muscle strength, and some patients may have trouble tolerating it.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Crohn disease inflammatory bowel disease Malnutrition nutritional deficiency disease Sarcopenia ulcerative colitis Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AOU Federico II

    RECRUITING

    Naples, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • IRCCS Humanitas

    RECRUITING

    Rozzano, Milano, 20089, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • IRCCS Policlinico San Matteo - Pavia

    RECRUITING

    Pavia, 27100, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ospedale Isola Tiberina - Gemelli Isola

    RECRUITING

    Roma, 00186, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••